Microbiology

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Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

From Institut Pasteur 23 Apr 2021

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Researchers have now identified how SARS viruses improve the production of viral proteins in infected cells such that new copies of the virus can be produced.

23 Apr 2021

Study offers new ways to think about the immune system

Scientists have discovered new methods to interpret the immune system, as part of a new study reported in the Nature journal.

21 Apr 2021

Sampling environmental DNA and RNA could help determine the presence of pathogens

Conventional techniques lack the potential to easily sample wider geographical areas and huge numbers of individuals.

21 Apr 2021

Antibodies may not inhibit SARS-CoV-2 variants from minks

It has been known for about a year that minks can become infected with SARS-CoV-2. The virus had been transmitted from humans to farmed mink and mutated in infected animals. Mutations were acquired in the spike protein, which is crucial for the entry of the virus into host cells and represents the central point of attack for antibodies.

20 Apr 2021

Supercomputer simulations reveal the behavior of dominant G form SARS-CoV-2 strain

Large-scale supercomputer simulations at the atomic level show that the dominant G form variant of the COVID-19-causing virus is more infectious partly because of its greater ability to readily bind to its target host receptor in the body, compared to other variants.

19 Apr 2021

New evidence of enriched rearing effects on well-being of aquaculture fishes

Collaborative research of the University of Jyvaskyla and Natural Research Institute Finland presents new evidence of the effects of enriched rearing on well-being of aquaculture fishes.

19 Apr 2021

INRS professor receives $700,000 for research on bacteria of the nasopharynx

Professor Frédéric Veyrier of the Institut national de la recherche scientifique (INRS) has received $711,450 from the Canadian Institutes of Health Research (CIHR) for a project on bacteria of the nasopharynx, including Neisseria.

16 Apr 2021

Study reveals how some antibodies can effectively disable ebolaviruses

Some survivors of ebolavirus outbreaks make antibodies that can broadly neutralize these viruses--and now, scientists at Scripps Research have illuminated how these antibodies can disable the viruses so effectively. The insights may be helpful for developing effective therapies.

16 Apr 2021

Ebola virus protein changes shape by using human RNA

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the protein's destined function. Tens of thousands of singular shapes drive the tens of thousands of needed functions.

15 Apr 2021

Scientists discover how immune response to TB differs in adults and newborn babies

The immune response to tuberculosis (TB) differs in adults and newborn babies due to the way immune cells use energy to kick into gear in a bid to kill the bacteria. This fresh discovery - just published in leading journal, Frontiers in Immunology - offers hope for improving treatments for what remains a deadly disease.

15 Apr 2021

Novel method to activate and visualize protein channels that keep bacteria alive

Almost all bacteria rely on the same emergency valves--protein channels that pop open under pressure, releasing a deluge of cell contents.

15 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

New simpler, faster system for analyzing mutations in SARS-CoV-2

Although it is known that mutations in the SARS-CoV-2 genome occurred and spread, the effect of those mutations is not yet clear.

From Osaka University 14 Apr 2021

New technique improves single-cell transcriptomics

With the help of single-cell transcriptomic techniques, researchers can study an unlimited number of individual cells from living organisms one at a time.

8 Apr 2021

Researchers discover new species of bumblebee through genome sequencing

Scientists have discovered a new species of bumblebees while investigating genetic diversity in bumblebees in the Rocky Mountains, United States.

8 Apr 2021

Study shows autism spectrum disorder is related to changes in the gut microbiome

According to a new study, autism spectrum disorder is associated with changes in the gut microbiome.

7 Apr 2021

Dopamine-releasing brain cells shed light on Parkinson’s disease

Scientists have found that botulinum toxin—commonly known as Botox—can expose the inner workings of the brain, in addition to smoothing out wrinkles.

From New York University (NYU) 7 Apr 2021

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

From UC San Diego 5 Apr 2021

Microbiology

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Study identifies mechanism that enables SARS viruses to efficiently replicate in infected cells

Study offers new ways to think about the immune system

Sampling environmental DNA and RNA could help determine the presence of pathogens

Antibodies may not inhibit SARS-CoV-2 variants from minks

Supercomputer simulations reveal the behavior of dominant G form SARS-CoV-2 strain

New evidence of enriched rearing effects on well-being of aquaculture fishes

INRS professor receives $700,000 for research on bacteria of the nasopharynx

Study reveals how some antibodies can effectively disable ebolaviruses

Ebola virus protein changes shape by using human RNA

Scientists discover how immune response to TB differs in adults and newborn babies

Novel method to activate and visualize protein channels that keep bacteria alive

Novel test detects HIV reservoir in patients more accurately

New simpler, faster system for analyzing mutations in SARS-CoV-2

New technique improves single-cell transcriptomics

Researchers discover new species of bumblebee through genome sequencing

Study shows autism spectrum disorder is related to changes in the gut microbiome

Dopamine-releasing brain cells shed light on Parkinson’s disease

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

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