Molecular & Structural Biology

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Scientists discover molecular mechanism that regulates the body's immune sentinels

A team at the Centro Nacional de Investigaciones Cardiovasculares, working in partnership with researchers at Mount Sinai Hospital in New York, has discovered a new molecular mechanism mediated by nuclear receptors that determines the identity and expansion of macrophages--one of the cell types that act as immune sentinels in the body.

6 Apr 2020

Making plant-based, protein-rich food to resemble meat

A team of University of Massachusetts Amherst food scientists has been awarded a grant from the Good Food Institute to create tasty, plant-based, protein-rich food that's similar in texture to whole chicken, pork or beef.

6 Apr 2020

Study designs artificial proteins that function as molecular logic gates

Researchers are currently using the same fundamental tools that enable the working of computers to manipulate life at the molecular level.

6 Apr 2020

Force can activate genes without intermediates, enzymes, or signaling molecules

A new study reports that cells tend to increase gene expression as a response to physical forces alone. According to the team, the initial step in the production of proteins—gene activation—begins within 1 ms once a cell gets stretched, which is hundreds of times faster than chemical signals can travel.

2 Apr 2020

New small molecules show promise for treating obesity and other disorders

Researchers have successfully identified novel compounds to prolong the period of the circadian clock and have also explained their mechanisms of action.

2 Apr 2020

Study tests the effect of deformation of microtubules in neurological conditions

Scientists develop a new approach to test the impact of the deformation of small cell proteins resembling a train track on their own function.

30 Mar 2020

Study reveals key mechanism behind DNA repair processes

According to a study recently published in the eLife journal, researchers have demonstrated a crucial mechanism involved in the repair processes of DNA double-strand breaks.

25 Mar 2020

eDNA tool can help assess biodiversity of species

Next-generation DNA sequencing has been used by Curtin University scientists to get a deeper understanding of different species of animals, insects, and plants existing in the Perth and Pilbara parts of Western Australia.

25 Mar 2020

Primitive bacterial parasites were first to use CRISPR to combat against one another

Humans are not the first to leverage the benefits of CRISPR. Pioneering research at the University of Copenhagen (UCPH) has enabled redefining what CRISPR is.

25 Mar 2020

Researchers discover the RNA editing process in squids

Researchers have recently discovered that squid can vastly edit their own genetic instructions, inside the nucleus of their neurons and also inside the axon.

24 Mar 2020

New method for mapping the structures of heparan sulfate sugars

Heparin, the blood-thinning drug, is used worldwide. However, to date, mapping of the fundamental sugar structures of heparin and the wider class of heparan sulfate sugars in cells has not been accomplished.

23 Mar 2020

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

G protein-coupled receptors (GPCRs) have crucial roles to play in cell signal transduction and can be used as vital therapeutic targets for several diseases.

20 Mar 2020

Genetically manipulating cells using synthetic materials to construct artificial structures

Researchers at the Stanford School of Engineering have designed a technique for reprogramming cells to use synthetic materials, which the team provides, to create artificial structures that can perform functions within the body.

20 Mar 2020

Role of MCL1 in maintaining intestinal homeostasis

An international group of scientists from the University of Zurich, the University Hospital Zurich, Heidelberg, and Glasgow have discovered a new function of MCL1, the protein that regulates cell death.

19 Mar 2020

IL-2's flexible structure helping the immune system

Scientists have known that interleukin-2 (IL-2), a signaling molecule, strongly influences the immune system. However, attempts to leverage its potential for therapeutic purposes have went futile due to serious side effects.

From University of California Santa Cruz 18 Mar 2020

Study finds fatty acid uptake is greater in cells that lack EHD2 protein

Several foods such as mozzarella on a pizza, the olive oil in salad dressing, or hollandaise sauce used on asparagus contain lots of fat.

18 Mar 2020

Two brain-signaling molecules control how male anemonefish care for and defend their young

A new study shows that two brain-signaling molecules regulate how male anemonefish care for their young ones and react to nest invaders.

17 Mar 2020

Hero proteins can prevent dangerous clumps linked with neurodegenerative diseases

At the University of Tokyo (UTokyo), scientists have identified a new group of proteins that have been hailed for their extraordinary shape and potential to defend against protein clumps linked with neurodegenerative diseases in laboratory experiments.

13 Mar 2020

Biochemical, analytical high-throughput methods used to map proteome of plants

Plants play a crucial role in the survival of life on earth. They offer oxygen for breathing and food for all organisms, as well as regulate the planet’s climate. Proteins are vital in controlling all aspects of life, including plants.

13 Mar 2020

Study identifies that the JNK protein is a stress sensor in synapses

Synapses are minute cell projections through which electrochemical impulses are transferred between nerves.

12 Mar 2020

Molecular & Structural Biology

Scientists discover molecular mechanism that regulates the body's immune sentinels

Making plant-based, protein-rich food to resemble meat

Study designs artificial proteins that function as molecular logic gates

Force can activate genes without intermediates, enzymes, or signaling molecules

New small molecules show promise for treating obesity and other disorders

Study tests the effect of deformation of microtubules in neurological conditions

Study reveals key mechanism behind DNA repair processes

eDNA tool can help assess biodiversity of species

Primitive bacterial parasites were first to use CRISPR to combat against one another

Researchers discover the RNA editing process in squids

New method for mapping the structures of heparan sulfate sugars

Study offers detailed molecular map of interaction patterns of GPCR and different G protein subtypes

Genetically manipulating cells using synthetic materials to construct artificial structures

Role of MCL1 in maintaining intestinal homeostasis

IL-2's flexible structure helping the immune system

Study finds fatty acid uptake is greater in cells that lack EHD2 protein

Two brain-signaling molecules control how male anemonefish care for and defend their young

Hero proteins can prevent dangerous clumps linked with neurodegenerative diseases

Biochemical, analytical high-throughput methods used to map proteome of plants

Study identifies that the JNK protein is a stress sensor in synapses

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