Proteomics

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Bioinformatics expert to design antibody-antigen interface to predict peptide sequences

Dmitri Klimov, Professor, Bioinformatics and Computational Biology, is creating a computational platform for designing an antibody-antigen interface based on DNA origami.

19 Oct 2020

A new protein discovered that repairs DNA

Researchers have identified a new protein that makes it possible to repair DNA. The protein in question is called cryptochrome.

15 Oct 2020

Two proteins compete to give shape to plants

In an elegant choreography, plants take cues from their environment and channel them into flowers, roots, or branches.

13 Oct 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

New index relies on pigs to demonstrate protein quality for humans

Nearly a decade ago, the UN's Food and Agriculture Organization (FAO) developed a new index to assess protein quality in foods. The goal, writ large, was to address food security for the world's most vulnerable populations, creating more accurate tools for food assistance programs seeking to provide balanced nutrition.

24 Sep 2020

Making healthy, environmentally friendly protein from the air

Increasing environmental challenges have led scientists to rethink how protein can be produced. Traditional processes require a lot of space on land or sea, resulting in a high carbon footprint and reduced resources.

24 Sep 2020

Researchers create an algorithm that predicts allosteric sites in proteins

A new technology that uses a protein's structure to predict the inner wiring that controls the protein's function and dynamics is now available for scientists to utilize.

4 Sep 2020

Study shows how high-protein diet protects against fatty liver

Non-alcoholic fatty liver disease is the most common chronic liver disease in the world, with sometimes life-threatening consequences.

19 Aug 2020

Protective anti-prion antibodies found in humans

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies.

18 Aug 2020

Scientists discover bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

18 Aug 2020

Protein produced by nervous system may be the key to treating inflammatory diseases

A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

From Rutgers University 18 Aug 2020

Study identifies a protein that facilitates spread of SARS-CoV-2 virus through cells

Eric Ross and Sean Cascarina, biochemistry and molecular biology researchers at Colorado State University, have released a research paper identifying a protein encoded by SARS-CoV-2, the virus that causes COVID-19, that may be associated with the quick spread of the virus through cells in the human body.

13 Aug 2020

Adaptive parallel mutations are more common in Lake Baikal amphipods

A group of scientists from Skoltech and the Institute for Information Transmission Problems of RAS (IITP RAS) showed, using Lake Baikal amphipods as an example, that parallel evolution driven by adaptations can be detected at the whole-genome level.

11 Aug 2020

New technology captures common biomarker of heart-disease

Researchers at the University of Wisconsin-Madison have developed a method combining sticky nanoparticles with high-precision protein measurement to capture and analyze a common marker of heart disease to reveal details that were previously inaccessible.

7 Aug 2020

Hudsonalpha researchers help elucidate functional elements of the genome

Although the Human Genome Project sequenced a nearly-complete human genome almost 20 years ago, only about two percent of the genes in the human genome have been extensively studied and identified as protein-coding genes. Proteins form the basis of living tissues and play a central role in biological processes.

3 Aug 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Buckwheat-based diet increases protein production that helps enhance longevity

A healthy low-calorie diet that contains plant products can help us improve the level of sirtuin 1 (SIRT1) protein production that is known to increase life expectancy.

23 Jul 2020

Archaeologists use new protein method to determine the sex of human remains

A new method for estimating the biological sex of human remains based on reading protein sequences rather than DNA has been used to study an archaeological site in Northern California.

21 Jul 2020

Newly discovered protein could be an important target to prevent prostate cancer metastases

Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases.

21 Jul 2020

Researchers find a way to prevent SARS-CoV-2 virus from binding to cells

On July 1, the Texas A&M Engineering Experiment Station's (TEES) National Center for Therapeutics Manufacturing (NCTM) received funding from the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) to help find a way to prevent the SARS-CoV-2 virus from binding to cells, protecting people from future infections.

20 Jul 2020