Antibodies and Immunology News and Research

Latest Antibodies and Immunology News and Research

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

According to a new study, a novel T cell genetically engineered by scientists from The University of Arizona Health Sciences can target and attack pathogenic T cells that are responsible for causing Type 1 diabetes. These latest findings may result in new immunotherapy therapies.

7 Dec 2020

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.

7 Dec 2020

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma, according to findings from a multi-institutional phase I study being presented by Alfred L. Garfall, MD, an assistant professor of Medicine in the division of Hematology-Oncology in the Perelman School of Medicine at the University of Pennsylvania, at the annual American Society of Hematology & Exposition Meeting on Dec. 5 (abstract #180).

7 Dec 2020

Gasdermin E triggers pyroptosis and involved in pathogen-induced coral death

Pyroptosis is a highly inflammatory form of programmed necrotic cell death that acts as a defense mechanism against the infection of bacterial and viral pathogens. Pyroptosis is executed by gasdermin, a family of pore-forming proteins.

7 Dec 2020

Researchers use super-resolution microscopy to study bacterial infection mechanisms

Expansion microscopy, abbreviated as ExM, allows scientists to image cells and their components with a spatial resolution down to 200 nm.

4 Dec 2020

Study explains new associations between Neanderthal DNA and autoimmune diseases

A researcher at the University of Tartu described new associations between Neanderthal DNA and autoimmune diseases, prostate cancer and type 2 diabetes.

4 Dec 2020

Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

3 Dec 2020

Researchers determine role of NLRP1 protein in detecting the common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

From Nanyang Technological University Singapore (NTU Singapore) 3 Dec 2020

Study shows metabolic state of disease-causing parasite influences its resistance to drugs

A new study has revealed how a disease-causing parasite is able to resist the present range of therapies. The study was recently published in eLife.

2 Dec 2020

New patented technique reveals the energy status of cells

Scientists have developed a novel process that may help personalize anticancer treatments.

2 Dec 2020

Study: Painkillers interfere with auxin flow essential for developmental processes in plants

For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin.

2 Dec 2020

Study: Gut microbiota directly shapes the makeup of human immune system

In recent years, the microbiota -- the community of bacteria and other microorganisms that live on and in the human body -- has captured the attention of scientists and the public, in part because it's become easier to study. It has been linked to many aspects of human health.

1 Dec 2020

Scientists successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Study underlines the significance of epithelial against invasive pathogens

Researchers have demonstrated that a protein present in skin cells detects a particular nucleic acid that is developed at the time of virus replication.

30 Nov 2020

UofL researcher finds less toxic way to deliver medicines

University of Louisville researchers have found a less toxic way to deliver medicines by using the natural lipids in plants, particularly grapefruit and ginger.

30 Nov 2020

Research provides new insight into how the CRISPR immune system evolved

With new insights into how the genetic tool CRISPR - which allows direct editing of our genes - evolved and adapted, we are now one step closer to understanding the basis of the constant struggle for survival that takes place in nature. The results can be used in future biotechnologies.

26 Nov 2020

Study shows how bacteria develop resistance to antibiotics

A group of researchers has successfully evolved the common microorganisms Escherichia coli at the experimental level.

25 Nov 2020

Study explains why immunotherapy works on certain patients with head and neck cancer

Researchers have found new clues about why certain individuals with head and neck cancer are able to respond to immunotherapy, while others fail to do so.

25 Nov 2020

Scientists identify key biological switch used in plant defense against animal attack

For decades, scientists have known that plants protect themselves from the devastation of hungry caterpillars and other plant-munching animals through sophisticated response systems, the product of millions of years of evolution.

From UC San Diego 25 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

Antibodies and Immunology News and Research

Latest Antibodies and Immunology News and Research

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

Gasdermin E triggers pyroptosis and involved in pathogen-induced coral death

Researchers use super-resolution microscopy to study bacterial infection mechanisms

Study explains new associations between Neanderthal DNA and autoimmune diseases

Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers determine role of NLRP1 protein in detecting the common cold virus

Study shows metabolic state of disease-causing parasite influences its resistance to drugs

New patented technique reveals the energy status of cells

Study: Painkillers interfere with auxin flow essential for developmental processes in plants

Study: Gut microbiota directly shapes the makeup of human immune system

Scientists successfully edit SIV virus from genomes of non-human primates

Study underlines the significance of epithelial against invasive pathogens

UofL researcher finds less toxic way to deliver medicines

Research provides new insight into how the CRISPR immune system evolved

Study shows how bacteria develop resistance to antibiotics

Study explains why immunotherapy works on certain patients with head and neck cancer

Scientists identify key biological switch used in plant defense against animal attack

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

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