Antibodies and Immunology News and Research

Latest Antibodies and Immunology News and Research

New type of cancer immunotherapy trains the immune system to eliminate tumor cells

A groundbreaking new type of cancer immunotherapy developed at the Icahn School of Medicine at Mount Sinai trains the innate immune system to help it eliminate tumor cells through the use of nanobiologics, tiny materials bioengineered from natural molecules that are paired with a therapeutic component, according to a study published in Cell in October.

2 Nov 2020

“Nanobiologic” immunotherapy can train the immune system to eliminate tumor cells

Until recently, it was believed that the innate immune system, the body's first line of defense, lacked the ability to remember pathogens like the adaptive immune system.

2 Nov 2020

Study identifies genes and molecular pathways most sensitive to chemical exposures

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

Scientists develop novel microcarrier for large-scale cell production

Researchers from Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a novel microcarrier for large-scale cell production and expansion that offers higher yield and cost-effectiveness compared to traditional methods, and reduces steps required in the cell retrieval process.

30 Oct 2020

SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Human immune system may play a key role in shaping the microbiome composition

The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch.

30 Oct 2020

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

30 Oct 2020

'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Myeloid cell can suppress the immune response to tumor cells

For a long time, researchers had believed that the brain reduces inflammation by protecting itself from an aggressive immune response.

28 Oct 2020

Scientists use new model to develop specific cancer immunotherapy

The function of the body’s immune system is to defeat diseases by detecting foreign invaders and then mounting a response against these pathogens.

28 Oct 2020

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020

Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020

Serologic testing of COVID-19 patients as an adjunct diagnostic method

A recent paper explored the possibility of using serologic testing as an adjunct diagnostic method in the diagnosis of SARS-CoV-2 infection.

28 Oct 2020

Study sheds new light on penicillin allergy

Scientists have reported the first strong evidence of the role of HLA-B, a crucial histocompatibility complex gene, in penicillin allergy.

27 Oct 2020

Anti-inflammatory mediator could play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Researchers identify genes associated with autism spectrum disorder

The lack of some genes in the BEC/TCEAL cluster could be related to some alterations associated with the autism spectrum disorder, according to a preclinical study published in the journal Genome Biology, and led by Professor Jordi Garcia Fernàndez, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and researcher Jaime Carvajal, from the Andalusian Centre for Developmental Biology - University Pablo de Olavide (CSIC-UPO).

27 Oct 2020

Researchers discover new ways to block the colonization and spread of tumor cells

What role do the lymphatic vessels play in the metastasis of cancer cells? Scientists from the German Cancer Research Center and the Mannheim Medical Faculty of the University of Heidelberg developed a method to investigate this question in mice.

27 Oct 2020

Researchers reveal the features of T cells for treating multiple sclerosis

Multiple sclerosis (MS) is an autoimmune disorder that develops as immune cells attack the nervous system. T cells are a critical part of our immune system, with a complex array of subtypes - some drive the autoimmune response, while others try to suppress it.

27 Oct 2020