Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Genetic Analysis Sheds Light on How Staphylococcus aureus Evades the Immune System

The most detailed study to date on the mechanisms by which a common type of bacterium, Staphylococcus aureus, adapts to living on the human body could help improve the prevention, diagnosis, and treatment of certain infections.

15 Jan 2025

New Genetic Risk Factor Identified for SARS-CoV-2 Infection

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus' ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.

15 Jan 2025

Base Editing Technique Extends Lifespan in Prion Disease Mouse Model

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Understanding RapA's Function in E. coli R-loop Control

From a genetic perspective, it is the worst-case scenario for a bacterium: during transcription, freshly created RNA adheres to its DNA template to form a three-stranded structure called an R-loop.

15 Jan 2025

Exploring the Therapeutic Potential of Copper Against Bacteria

A researcher at the University of Arizona College of Medicine in Tucson was awarded a $1.9 million grant by the National Institutes of Health to carry out more research on the mysteries of copper, particularly how it can be used to eradicate dangerous bacteria and other microorganisms.

13 Jan 2025

Is it possible to predict a pathogen’s next move? Novel tool for detecting pathogen fitness says yes!

Phylowave reveals evolutionary dynamics in pathogens, identifying fitness-linked lineages and mutations, essential for effective public health interventions.

13 Jan 2025

Scientists Uncover Key Plant Metabolite to Block Biofilm Development

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

13 Jan 2025

Researchers Discover How Protein Instability Drives Heritable Diseases

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature.

10 Jan 2025

Scientists Uncover Circuit Controlling Neuron Migration in Brain Development

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

10 Jan 2025

Fiber Digestion Alters Gene Function with Potential Anti-Cancer Effects

Fiber is well known to be an important part of a healthy diet, yet less than 10% of Americans eat the minimum recommended amount.

10 Jan 2025

UK Biobank to Study Protein Changes Across 600,000 Samples

UK Biobank has today announced the launch of the world's most comprehensive study of the proteins circulating in our bodies, which will transform the study of diseases and their treatments.

10 Jan 2025

Novel Targets for Modulating the Gut Microbiota and Human Health

Researchers at the Helmholtz Institute for RNA-based Infection Research and the Julius-Maximilians-Universität in Würzburg have discovered a protein and a class of small ribonucleic acids (sRNAs) in Bacteroides thetaiotaomicron that control the metabolism of sugar.

10 Jan 2025

Arabidopsis Study Finds that Centromeres Call the Shots in Retrotransposon Integration

Centromeres play a crucial role in cell division, with CENH3 guiding retrotransposon Tal1 integration, revealing insights into genome evolution and stability.

10 Jan 2025

New Insights into How Nitrogenase Enzyme Survives Oxygen Exposure

Nitrogen is an essential component in the production of amino acids and nucleic acids - both necessary for cell growth and function.

9 Jan 2025

Echidna Genome Sheds Light on Complex Sex Chromosome Evolution

A nearly gapless genome sequence of the echidna, an egg-laying mammal with multiple sex chromosomes, helps researchers to track genomic reorganization events that gave rise to a highly unusual sex determination system.

9 Jan 2025

Identifying PRIMER Cells and their Role in Defense Signaling

A diverse population of immune cells that move from one organ to another and react to anything from cuts to colds to cancer is how human bodies protect themselves. However, this luxury is not available to plants.

9 Jan 2025

How Streptomyces Uses Iron to Target Competitor Bacteria

Researchers at Indiana University Bloomington have identified a new mechanism by which bacteria can eliminate their competitors within intricate microbial communities, highlighting innovative strategies to utilize viruses for targeting harmful bacteria.

9 Jan 2025

Mapping the Aging Brain: A Single-Cell View of Transcriptomic Changes

Research reveals how aging impacts gene expression across brain cell types, identifying critical changes in the hypothalamus linked to health and function.

9 Jan 2025

Weak Molecular Interactions Trigger Autophagy in Cells

Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks.

8 Jan 2025

New Insights into Nuclear Lipid Droplets as Regulators of Aging and Metabolic Health

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled "Nuclear lipid droplets: a novel regulator of nuclear homeostasis and aging."

8 Jan 2025