Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

Chemotherapy and radiotherapy aim to destroy cancer cells by inducing DNA double-strand breaks – damage that, once inflicted, usually causes the cells to die. But damage to a cell's genetic material also activates a signaling pathway called IKK/NF-κB that helps prevent cell death, thus limiting the success of these treatments in patients.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

New Method Facilitates Early Detection and Localization of Tumors

To help with early tumor diagnosis and tumor localization, researchers have devised a technology that concurrently detects many cancer-specific DNA circulating hallmarks.

26 Jul 2023

Looking at Protein Function in Preventing Female Obesity

Obesity is on the rise in the US, which is linked to worse health outcomes and a lower quality of life. Over 30% of American individuals are currently considered fat. Obesity is a significant and expanding public health issue since it is a risk factor for several diseases, including diabetes, cardiovascular disease, and COVID-19.

26 Jul 2023

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

The University of Texas MD Anderson Cancer Center and Nexo Therapeutics today announced a multi-year strategic collaboration that aligns the innovative technology and capabilities of each organization at the earliest stages of drug discovery and development to rapidly advance impactful new cancer therapies against previously undruggable targets.

26 Jul 2023

Researchers Design New Algorithm to Boost Pandemic Preparedness

Immune system researchers have designed a computational tool to boost pandemic preparedness. Scientists can use this new algorithm to compare data from vastly different experiments and better predict how individuals may respond to disease.

26 Jul 2023

Towards Artificial Photosynthesis with Engineering of Protein Crystals in Bacteria

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

BioMap Unveils a "Life Science Leaderboard" to Compare AI Models and Reveals the Advanced Capabilities of its 100B-Scale "xTrimo" Model

BioMap, a company with an AI foundation model powered life science platform, today announces the official launch of the “Life Science Leaderboard” – a living resource for industry professionals and researchers to evaluate the performance of life science AI models.

26 Jul 2023

Identifying The Best Antibodies Using X-Rays

Imagine you're going to a party where you only know a single person. While you've been friends with this person for a long time, you're concerned about them leaving you alone in a room full of strangers. Even though they promise they'll stick by your side, they immediately walk away from you upon entering the party to speak to someone else they know.

26 Jul 2023

New Class of Brain Inhibitory Neurons May Contribute to Autism and Schizophrenia

A University of California, Irvine-led team of researchers working at the Center for Neural Circuit Mapping find links between brain disorders and dysfunction of newly identified inhibitory brain cell types.

26 Jul 2023

In-Cell Engineering Proves to be a Powerful Tool for Synthesizing Functional Protein Crystals

In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech.

26 Jul 2023

Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

'Orphan' Gene may Have Evolved to Give Seahorses Their Unique Brood Pouch

Teleost fish encompass a diverse group, among which seahorses display a unique morphology. The characteristic spines and brood pouch seen in seahorses feature distinctive epithelial cells-;called flame cone cells-;covered by a mucous cap.

25 Jul 2023

Breakthrough in Single-Cell Genome Sequencing: New Method Reduces Bias and Expands Research Horizons

It has long been technically difficult to sequence the genome of a single bacterial cell due to the nearly impossible bias in the gene amplification stage of the process, making it difficult to produce a high-coverage genome sequence from precisely one bacterial cell.

25 Jul 2023

Dietary Fiber Regulates Gut Microbiota and Improves Epithelial Cell Proliferation

A high-fiber diet is known to have several health benefits. Scientific studies point to protection against such diseases as cancer and diabetes.

25 Jul 2023

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Oxidative stress, caused by an imbalance of free radicals and antioxidants, regularly reduces the yield of pharmaceuticals and therapeutics produced via bioprocessing by about 10-15%. Now, Xheme, Inc.'s Xheme Multifunctional Additive (XMA), a programmable non-toxic nanoporous microparticle, has demonstrated the ability to significantly reduce or eliminate the damage of oxidative stress in bioprocessing conditions.

25 Jul 2023

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

Sensing and communicating with the extracellular environment are both aspects of transmembrane signaling.

24 Jul 2023

The Evolutionary Enigma: Unraveling the Origins of Seahorses' Flame Cone Cells

A brood pouch in male fish and bony plates gives seahorses their distinctive shape.

24 Jul 2023

New Protein Found to be Key to Proper Functioning of Acinar Cells

The energy supply in the body has been regulated by the pancreas, located behind the stomach. This mechanism happens by secreting proteins (enzymes) accountable for glucose–the body’s primary fuel–reaching other organs when needed and in the exact amount.

24 Jul 2023

New Method for Building Modular Optical Sensors to Detect Bacteria and Viruses

An innovative method for building modular optical sensors that can detect viruses and bacteria has been created by an interdisciplinary research team from Bochum, Duisburg, and Zurich.

24 Jul 2023

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Analyzing DNA Damage-Induced NF-κB Targeted by Novel Small Molecule Inhibitors

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

New Method Facilitates Early Detection and Localization of Tumors

Looking at Protein Function in Preventing Female Obesity

New Collaboration Aims to Advance Cancer Therapies Against Previously Undruggable Targets

Researchers Design New Algorithm to Boost Pandemic Preparedness

Towards Artificial Photosynthesis with Engineering of Protein Crystals in Bacteria

BioMap Unveils a "Life Science Leaderboard" to Compare AI Models and Reveals the Advanced Capabilities of its 100B-Scale "xTrimo" Model

Identifying The Best Antibodies Using X-Rays

New Class of Brain Inhibitory Neurons May Contribute to Autism and Schizophrenia

In-Cell Engineering Proves to be a Powerful Tool for Synthesizing Functional Protein Crystals

Lactate Signaling Found to Be Critical for Neuronal Differentiation

'Orphan' Gene may Have Evolved to Give Seahorses Their Unique Brood Pouch

Breakthrough in Single-Cell Genome Sequencing: New Method Reduces Bias and Expands Research Horizons

Dietary Fiber Regulates Gut Microbiota and Improves Epithelial Cell Proliferation

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

The Evolutionary Enigma: Unraveling the Origins of Seahorses' Flame Cone Cells

New Protein Found to be Key to Proper Functioning of Acinar Cells

New Method for Building Modular Optical Sensors to Detect Bacteria and Viruses

Omics eBook

The Exclusome, A New Mammalian "Containter"

Breaking Down the Onso System: PacBio's Genomic Advancement

The Last Piece of Our Genome: Sequencing the Y Chromosome

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

The Exclusome, A New Mammalian "Containter"

Breaking Down the Onso System: PacBio's Genomic Advancement

The Last Piece of Our Genome: Sequencing the Y Chromosome

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