Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

mRNA Vaccine Supercharges Immunotherapy Against Cancer

An experimental mRNA vaccine improved the tumor-fighting benefits of immunotherapy in a mouse model study, bringing researchers one step closer to their aim of generating a universal vaccination to “wake up” the immune system against cancer.

21 Jul 2025

Brain Cells Show Unexpected Self-Sufficiency in Energy Use

A new Yale study has revealed that neurons - the energy-hungry cells that connect and direct activity in the brain - are equipped with "backup batteries" that kick in to keep the brain running during periods of metabolic stress.

18 Jul 2025

Simple Models Reveal Soil’s Complex Microbial Conversations

Just like any living organism, the soil has its own metabolism. Plants, worms, insects, and most importantly, microorganisms in the soil, break down organic matter, consume and generate nutrients, and process other materials to give the soil a life of its own.

18 Jul 2025

Molecular Chatter Between Cells Drives Tumor Growth and Immune Suppression

A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary metabolic processes, program one set of noncancerous cells to manipulate another set of such cells to support their growth and survival.

18 Jul 2025

GlycoPro Platform Enhances High-Throughput Glycosylation Analysis

A recent study published in Engineering introduces GlycoPro, a novel high-throughput sample-processing platform that aims to transform the field of multi-glycosylation-omics analysis.

18 Jul 2025

Gut Bacteria Adapt to Local Diets Offering Hope for Personalized Probiotics

Probiotics are emerging tools used by neonatal intensive care units to promote healthy outcomes and prevent intestinal diseases such as necrotizing enterocolitis.

18 Jul 2025

Synthetic Cells Offer New Clues About the Origins of Life

At some point during the evolution of life on Earth, inorganic matter became organic, nonliving matter became living. How this happened is one of humankind's greatest mysteries.

18 Jul 2025

Amino Acids Guide Cell Responses to Drugs Through a Complex Network

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure.

17 Jul 2025

New Metabolic Map Reveals How Blood Stem Cells Age and Become Diseased

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous.

16 Jul 2025

New Computational Tool Enhances Gene Discovery in Heart and Metabolic Diseases

Genetic changes can signal evidence of disease, but pinpointing which genes and what's changed can be difficult.

16 Jul 2025

Regulators of Cancer Cell Communication During Invasion

This study identifies key genes regulating neural crest functions in melanoma, revealing insights into collective migration and potential therapeutic targets.

16 Jul 2025

MiROM Uses Infrared Light to Detect Protein Changes in Single Cells

MiROM identifies proteins by using mid-infrared light to detect molecular vibrations – essentially the natural "dance" of molecules within protein structures.

16 Jul 2025

New Research Reveals Key Protein Behind Plant Heat Tolerance

While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It's a question many have wondered-and now, science has an answer.

15 Jul 2025

Paternal miRNAs Play Unexpected Role in Seed Viability and Embryogenesis

By using targeted gene silencing in different pollen cell types, the study reveals that disrupting DCL1 function either in the vegetative cell or in sperm cells leads to defective seed formation.

14 Jul 2025

Researchers Uncover Complex Substrate Profile for Enzyme Action

Research on γ-secretase reveals its unique substrate recognition mechanism, offering potential for developing precise therapeutic agents for various diseases.

14 Jul 2025

Understanding DNA's Complex 3D Architecture in the Cell

Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying cancer and muscular dystrophy.

14 Jul 2025

Rutgers Scientists Uncover Protein Key to Learning and Memory

Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for learning and memory.

14 Jul 2025

UAB Identifies Six Novel Subsets, Reshaping Immune Knowledge

The study highlights T-bet's importance in memory B cells, essential for rapid antibody production and sustained immune defense against influenza.

14 Jul 2025

New Microchip Maps Antibody Responses Using Just a Drop of Blood

A new microchip invented by Scripps Research scientists can reveal how a person's antibodies interact with viruses-using just a drop of blood.

14 Jul 2025

LINE1 Retrotransposon Found to Exploit Dormant Protein in Human Cells

An international research team led by Freiburg biologists Dr. Wenjing Qi and Prof. Ralf Baumeister has discovered how the LINE1 retrotransposon exploits a cell protein to become active itself, as occurs in tumors.

14 Jul 2025