Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

High-Resolution Map Exposes Cellular Pathways to Fertility

An interdisciplinary team mapped the gene expression that takes place in mice during follicle maturation and ovulation using a state-of-the-art method of RNA tagging.

24 Jan 2024

Unveiling the Design Principles of Gene Regulatory Networks

Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.

24 Jan 2024

LambdaVision Aims to Refine Process for In-Space Manufacturing of Artificial Retinas Through ISS National Lab-Sponsored Investigation

Approximately 1.5 million people worldwide are affected by retinitis pigmentosa, a rare genetic disorder that causes vision loss.

24 Jan 2024

Genomic Insights Into the Evolution of Gigantism in Cetaceans

Certain gene regions in cetaceans (whales, porpoises, and dolphins) play a role in explaining the remarkable size differences among species, such as the Blue whale (Balaenoptera musculus), which can reach lengths of up to 30 m – almost 10 m longer than a bus – in contrast to the Bottlenose dolphin (Tursiops truncatus), which typically reaches a maximum length of 4 m.

23 Jan 2024

Boosting Central Memory T Cells with Targeted Protein Modulation

The Hackensack Meridian Center for Discovery and Innovation's (CDI) Xue Lab has made yet another advancement in the understanding of the immune system and its potential for disease-fighting modulation.

22 Jan 2024

Phage Proteins Tame CRISPR-Cas3, Paving Way for Precise Gene Therapy

Through the use of CRISPR, an immune system that bacteria use to defend themselves against viruses, researchers have been able to alter genetic information within cells.

22 Jan 2024

New Virus Targets Dormant Bacteria, Boosting Antibiotic Power

In nature, the majority of bacteria adhere to a minimalistic lifestyle. When faced with nutrient scarcity or stress, they initiate a controlled shutdown of their metabolism, entering a resting state.

22 Jan 2024

DNA Repair Breakthrough: Scientists Reveal RecA's Precise Helix Navigation

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling single-strand end into intact double strands, and repairing the break based on the undamaged sequence.

22 Jan 2024

Glowing COVID-19 Diagnostic Test Prototype Produces Results in One Minute

Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical?

19 Jan 2024

Golgi Organelle's Crucial Role in Stress Responses

For more than a century, scientists have been aware of a certain organelle found in plant cells. That organelle's crucial function in aging, however, has only recently been uncovered by UC Riverside scientists.

18 Jan 2024

Study Uncovers Chromatin Modifier-Centered Pathway for Grain Size Regulation in Rice

Chromatin is the complex of DNA and proteins that makes up the genetic material in the nucleus of eukaryotic cells.

18 Jan 2024

USC Scientists Discover Protein Key to 3D Genome Control and Gene Silencing

Each cell’s nucleus contains DNA, which is the blueprint for human life.

17 Jan 2024

Investigating the Functional Mechanisms of RNA Replicase

It has long been a mystery how the complex molecular machinery of life sprang from modest beginnings.

17 Jan 2024

The Role of Diffusion Barriers in Cellular Functions

According to a recent paper published in the “Journal of Cell Biology” by the Barral group (IBC), diffusion barriers are established by mitochondria independently of physical separation.

16 Jan 2024

Genome-Wide Study Identifies Gene Pair Crucial for Regulating Blood Vessel Disease in the Lungs

University of Pittsburgh Schools of Medicine researchers uncovered a fundamental mechanism that controls the body's response to limited oxygen and regulates blood vessel disease of the lung.

16 Jan 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Honeybees Directly Provide Nutrients to Gut Bacteria

Bacteria have adapted to all terrestrial environments. Some have evolved to survive in the gut of animals, where they play an important role for their host; they provide energy by degrading indigestible food, they train and regulate the immune system, they protect against invasion by pathogenic bacteria, and they synthesize neuroactive molecules that regulate the behavior and cognition of their host.

16 Jan 2024

Messenger RNA Therapy Could be Used to Correct Rare Liver Genetic Disease

By exploiting the technology used in Covid-19 vaccines, a team led by UCL, King's College London and Moderna scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology's potential therapeutic use in people.

16 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024