Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Breakthrough Gene Discovery Uncovers a Master Switch for Food Intake

The Gpr45 gene is linked to food intake regulation, offering insights for obesity therapies. Study utilizes Automated Meiotic Mapping for gene identification.

6 Jun 2025

Newly Identified Molecules from Blood Bacterium Show Promise in Combating Skin Aging

Indole metabolites from the blood bacterium P. sanguinis demonstrate potential in anti-aging skin treatments by lowering inflammation and oxidative damage.

6 Jun 2025

Chitin Facilitates Gene Transfer Across Species Through Natural Transformation Among Vibrio cholerae

A study in PNAS reveals that chitin promotes gene transfer in marine environments by binding environmental DNA and enhancing natural transformation in Vibrio cholerae, with implications for microbial evolution and ecosystem diversity.

6 Jun 2025

Camelina Breakthrough Could Transform Natural Astaxanthin Production

In a major step forward for sustainable pigment production, scientists have successfully engineered the oilseed crop Camelina sativa to produce high levels of astaxanthin — a valuable red antioxidant used to color farmed salmon and shrimp — using plant-derived genes rather than bacterial pathways.

6 Jun 2025

UC Davis Study Links Specific microRNAs to Mental and Neurological Disorders

A study in Nature Aging from researchers at the UC Davis School of Medicine has identified specific microRNAs - non-coding RNAs that regulate gene expression within cells - that likely contribute to bipolar disorder, depression, schizophrenia, post-traumatic stress disorder (PTSD) and Parkinson's disease.

5 Jun 2025

Base Editing Breakthrough Brings Hope for Genetic Disease Treatment

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation.

5 Jun 2025

Novel RNAs from Jumping Genes Produce Reverse Transcriptase Activity in Aging Neurons

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older.

5 Jun 2025

PPP2R1A Gene Mutations Improve ATR Inhibitor Drug Effectiveness in Ovarian Clear Cell Cancers

A study in Oncogene shows that PPP2R1A mutations increase sensitivity to ATR inhibitors in ARID1A-mutant ovarian clear cell carcinoma, suggesting a potential biomarker for improved treatment strategies.

5 Jun 2025

New Study Details H9N2 Avian Flu’s Variability and Public Health Implications

Research on H9N2 avian influenza shows extensive genetic changes, raising public health concerns and emphasizing the need for enhanced monitoring and vaccines.

4 Jun 2025

Key Factor in Pancreatic Cancer Cell Survival in Distinct Environments

Scientists at the University of California, San Francisco, have found how pancreatic cancer cells grow in the lungs or liver, which are as different from cells as the ocean and the desert are to animals.

4 Jun 2025

Blocking Viral Enzyme Boosts Brain Immunity Against HSV-1

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

4 Jun 2025

Study Reveals Key Proteins Behind CAR-T Cell Therapy Effectiveness

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Exon-Specific Analysis Uncovers Novel Insights into Psychiatric Disease

This research highlights the role of exons in mental illnesses, offering new perspectives on genetic factors that influence psychiatric disorder development.

3 Jun 2025

New Genome Assembly Sheds Light on Tropical Vine's Invasive Success

Merremia boisiana, a member of the Convolvulaceae family, a fast-growing vine native to tropical rainforests and known for its vibrant golden flowers and astonishing climbing ability, grows at speeds exceeding 12 cm per day, often overwhelming native vegetation and disrupting forest ecosystems.

2 Jun 2025

Light-Controlled Phagobots Offer Precision Immune Modulation

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells.

2 Jun 2025

Cryo-EM/ET Reveals Dynamic Architecture of Key Metabolic Enzyme

Recent cryo-EM research reveals the dynamic architecture of the pyruvate dehydrogenase complex, enhancing understanding of its role in metabolism and disease.

2 Jun 2025

Repairing DNA Double-Strand Breaks May Improve Genomic Stability by Limiting Organelle-to-Nucleus Gene Transfer

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from organelles to the nucleus in plants. Disruption of DSBR increases the risk of genomic instability through endosymbiotic gene transfer (EGT).

2 Jun 2025

Exploring the Metabolic Pathways of Cancer Cells

Research from the University of Cincinnati reveals how the MYC oncogene alters PRPS enzymes, impacting redox homeostasis and lymphoma progression.

30 May 2025

New Insights into the Molecular Fight or Flight Reset

Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allows the body to react swiftly to stress or starvation.

30 May 2025

UVA Research Reveals Key to HIV Latency

University of Virginia School of Medicine scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.

30 May 2025