Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Gut microbes mitigate radiation exposure, repair GI tract

A new study by scientists at UNC Lineberger Comprehensive Cancer Center and colleagues published Oct. 30, 2020, in Science, showed that mice exposed to potentially lethal levels of total body radiation were protected from radiation damage if they had specific types of bacteria in their gut.

2 Nov 2020

Study identifies genes and molecular pathways most sensitive to chemical exposures

A University of Massachusetts Amherst environmental health scientist has used an unprecedented objective approach to identify which molecular mechanisms in mammals are the most sensitive to chemical exposures.

30 Oct 2020

SARS-Cov-2 spike proteins can directly impact the function of blood-brain barrier

Like a key, SARS-CoV-2 - the virus that causes coronavirus disease 2019 (COVID-19) - attaches to specific molecules on the host cell surface, opening gateways into the cell interior.

30 Oct 2020

Scientists discover new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule -- diphenylisoxazole. This molecule has been shown to be effective against human cancer cells. The research, published in the journal Bioorganic & Medicinal Chemistry Letters, makes it possible to produce an affordable cancer treatment drug.

30 Oct 2020

Researchers describe how drug use change specific brain cells responsible for motivation

In the October 28, 2020 issue of the Journal of Neuroscience, researchers from the Medical University of South Carolina and the National Institutes of Health describe how reminders of drug use can change specific brain cells responsible for motivation, increasing the desire to seek drugs.

30 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Sodium bicarbonate can reprogram T cells in leukemia patients

Scientists have discovered that sodium bicarbonate - also known as baking soda or bicarbonate of soda - can reprogram T cells in leukemia patients to resist the immune-suppressing effects of cancer cells, which can drive leukemia relapse after stem cell transplants.

29 Oct 2020

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Tangles of misfolded tau proteins in the brain are closely associated with memory loss in patients with Alzheimer's disease.

29 Oct 2020

Researchers develop RNA catalyst that sheds light on evolution

Enzymes enable biochemical reactions that would otherwise not take place on their own. In nature, it is mostly proteins that function as enzymes.

29 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Why a diet high in flavanols may lower blood pressure

In this interview, AZoLifeSciences speaks to Professor Kuhnle about his latest research which showed that a diet high in flavanols may lower blood pressure.

From University of Reading 28 Oct 2020

Myeloid cell can suppress the immune response to tumor cells

For a long time, researchers had believed that the brain reduces inflammation by protecting itself from an aggressive immune response.

28 Oct 2020

Study shows how cancer remodels human chromosomes for its own purposes

Scientists have shown that cancer rebuilds the architecture of human chromosomes, which allows the disease to take hold and spread.

28 Oct 2020

RNA-centric mechanism regulates microRNAs linked to cancer, neurological disorders

MicroRNAs are small non-coding RNAs—that is, bits of genetic code that act as key gene regulators in various aspects of biological processes.

28 Oct 2020

Researchers map molecular structure of CV30 antibody to neutralize coronavirus

Scientists at Fred Hutchinson Cancer Research Center in Seattle have shown that a potent antibody from a COVID-19 survivor interferes with a key feature on the surface of the coronavirus's distinctive spikes and induces critical pieces of those spikes to break off in the process.

28 Oct 2020

Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020