Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Novel method enables quick identification of small active substance molecules

Secondary natural substances that occur in numerous plants, bacteria and fungi can be anti-inflammatory, can ward off pathogens or even prevent the growth of cancer cells. However, making use of the riches provided by nature's medicine cabinet and identifying new natural substances is time-consuming, costly and labour-intensive. A team of bioinformaticians at Friedrich Schiller University Jena has now developed a method that enables much faster and easier identification of small active substance molecules.

18 Oct 2021

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

At the beginning of neurodegenerative disease, the immune cells of the brain – the "microglia" – take up glucose, a sugar molecule, to a much greater extent than hitherto assumed.

18 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Researchers refine cryogenic electron microscopy technique

In the late 1600s, the Dutch tradesman Anthoni van Leeuwenhoek began investigating the world of the very small using the first microscope, discovering a riotous world of protists, bacteria, and other previously unseen organisms.

18 Oct 2021

Study explores dietary supplementation with vitamin D to support cows’ immune function

Known as a crucial component in the body's ability to absorb and retain calcium, essential to processes such as the development and maintenance of healthy bones, vitamin D has also been found to play important roles in immune defense.

18 Oct 2021

New statistical study reveals the constraints and directions in protein evolution

A recent statistical study has revealed some of the constraints and directions in the evolution of the structure and function of proteins.

15 Oct 2021

Infection with measles virus activates two different immune responses

Researchers from The University of Tokyo Institute of Industrial Science have found that infection with the measles virus activates not one but two different branches of the innate immune system.

15 Oct 2021

Type A immunoglobulins play a key role in keeping the intestinal flora in balance

The bacteria living in the intestine consist of some 500 to 1000 different species. They make up what is known as the intestinal flora, which plays a key role in digestion and prevents infections.

15 Oct 2021

Study identifies DNA mutations that impact metabolism and insulin sensitivity in liver disease patients

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

15 Oct 2021

Molecular atlas of small cell lung cancer reveals signatures of metastasis and immunosuppression

Imagine you're about to go on a cross-country trip, stopping at spots along the way to admire local attractions.

15 Oct 2021

Researchers use photosynthetic microbes as an oxygen source for nerve cells

Each second, the nerve cells in the brain process numerous signals. And the energy needed to carry out these tasks is mostly generated by aerobic metabolism—the reason why the brain needs a constant supply of oxygen.

15 Oct 2021

Study identifies protein complex that confers neuroprotection against HSV-1 infection

Recent research by scientists from the University of Illinois demonstrates a process that halts the herpes simplex virus 1 from inducing severe brain damage and death.

15 Oct 2021

Researchers improve understanding of molecular mechanisms underlying stomach’s acid pump

Nagoya University researchers and colleagues have improved understanding of the molecular mechanisms of a key protein that makes the stomach acidic. Their findings, published in the journal Nature Communications, could lead to better drugs for stomach ulcers and shed light on the functions of similar proteins across the human body.

15 Oct 2021

Eating whole grain rye products is a better option than wheat for weight loss, finds study

Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits. Researchers at Chalmers University of Technology, Sweden, recently published a study showing that people who ate high-fibre products made from whole grain rye lost more body fat and overall weight than those who ate corresponding products made from refined wheat.

13 Oct 2021

Study explores the effects of epigenetic editing in various tumor settings

Recent research reports that the appropriate functioning of this mechanism is essential for tissue homeostasis and cell fate determination.

13 Oct 2021

Experts come up with a powerful tool for illustrating genome folding

The intricate folds and arrangements of protein and DNA bundles inside the microscopic boundaries of a single human cell instruct the fate of an individual

13 Oct 2021

Regulatory network impacting brain evolution found in “junk DNA,” says study

Human DNA has a close resemblance to that of the chimpanzee, which in evolutionary terms is the closest living relative of humans.

13 Oct 2021

Study provides insights on mucin degradation mechanisms by a group of gut bacteria

Recent research identified that a single sulfatase adds to the degradation of mucus that safeguards the intestinal lining.

13 Oct 2021

Research reveals involvement of secretory granules in Parkinson’s disease

Recent research states that the number of secretory granules (SGs) in tyrosine hydroxylase-positive neurons and the marker proteins secretogranin III substantially lowered in the substantia nigra and striatum regions of mice exposed to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine.

13 Oct 2021

Study details metabolic processes employed by SARS-CoV-2 to attack lung tissue

Scientists from the Karolinska Institutet discovered certain metabolic mechanisms that SARS-CoV-2 employs to attack lung tissue.

13 Oct 2021

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Novel method enables quick identification of small active substance molecules

Brain immune cells take up large amounts of sugar at the beginning of neurodegenerative disease

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Researchers refine cryogenic electron microscopy technique

Study explores dietary supplementation with vitamin D to support cows’ immune function

New statistical study reveals the constraints and directions in protein evolution

Infection with measles virus activates two different immune responses

Type A immunoglobulins play a key role in keeping the intestinal flora in balance

Study identifies DNA mutations that impact metabolism and insulin sensitivity in liver disease patients

Molecular atlas of small cell lung cancer reveals signatures of metastasis and immunosuppression

Researchers use photosynthetic microbes as an oxygen source for nerve cells

Study identifies protein complex that confers neuroprotection against HSV-1 infection

Researchers improve understanding of molecular mechanisms underlying stomach’s acid pump

Eating whole grain rye products is a better option than wheat for weight loss, finds study

Study explores the effects of epigenetic editing in various tumor settings

Experts come up with a powerful tool for illustrating genome folding

Regulatory network impacting brain evolution found in “junk DNA,” says study

Study provides insights on mucin degradation mechanisms by a group of gut bacteria

Research reveals involvement of secretory granules in Parkinson’s disease

Study details metabolic processes employed by SARS-CoV-2 to attack lung tissue

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Proteomics, Metabolomics and Lipidomics News and Research

Latest Proteomics, Metabolomics and Lipidomics News and Research

Omics eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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