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The Mechanism of Immune Memory Development

The memory of the immune system depends on distinctive epigenetic traits and a particular 3D arrangement of the DNA in the nucleus of memory cells, allowing for rapid activation of these cells, according to a team of researchers from the Erasmus University Medical Center, the Centre for Genomic Regulation (CRG), and the Josep Carreras Leukaemia Research Institute.

12 Jul 2023

Researchers Uncover Astonishing Diversity of Protein Structures Previously Unexplored

The astounding variety of protein structures and their folds in nature has been further illuminated by a ground-breaking discovery. Researchers wanted to know how much of the huge range of potential protein structures nature had examined.

12 Jul 2023

Fossil Record Can Be Used to Assess Health of Marine Ecosystems

Biologists attempting to conserve and restore denuded environments are limited by their scant knowledge of what those environments looked like before the arrival of humans.

12 Jul 2023

Lipe Gene Plays Pivotal Role in Retinal Health, Study Finds

UT Southwestern Medical Center researchers have identified a gene called Lipe that appears to be pivotal to retinal health, with mutations spurring immune activation and retinal degeneration.

12 Jul 2023

New Insights Into How Genes Are Activated

Genetic information contained within DNA has to be read by specific proteins that enable the process of gene activation to begin – but in many cases, these proteins can't access their targets because DNA strands are bundled up to control what genes are used in the wide range of different cell types.

12 Jul 2023

New Garra Species Discovered in Remote Thai River

With just a few clicks of a mouse, you can purchase your very own redtail garra, a type of fish that feeds on algae.

12 Jul 2023

Most Bacteria Found in European Kitchens Are Harmless

Bacteria found in 74 kitchens spread among 5 European countries were mostly harmless according to new research published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

12 Jul 2023

Glucose-Sensing Neurons May Play a Role in Regulating Blood Sugar

The body's blood glucose level needs to be maintained in a relatively narrow range. It cannot be too high, as it can lead to diabetes, and it cannot be too low because it can cause fainting or even death.

12 Jul 2023

Whole Genome Sequencing More Effective Than Targeted Gene Sequencing in Detecting Genetic Disorders

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

12 Jul 2023

Revolutionizing Drug Design with Light-Activated Molecular Machines

Cells “talk” to one another to coordinate crucial biological activities such as immune activation, muscle contraction, hormone release, neuronal firing, and digestion using calcium signaling as a primary mechanism.

11 Jul 2023

Live Broadcasting of “Growth Factor Signaling” Proteins Inside Living Cells

The “live reporter” technology, developed by synthetic biologists at Princeton University and Rice University, has shown that it is possible to expose, with a great deal more accuracy than is now possible, the functioning of networks of signaling proteins in living cells.

11 Jul 2023

AMP Releases CYP3A4 and CYP3A5 Genotyping Assay Recommendations

The Association for Molecular Pathology (AMP), the world’s leading professional society for molecular diagnostics, released consensus recommendations today to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, encourage standardization of testing across labs, and better patient care.

11 Jul 2023

Investigating the Seasonal Dynamics of the Wastewater Microbiome

The composition of the bacterial community in wastewater is influenced by the community of microbial predators. This describes seasonal variations in the microbial community that impact water treatment efficacy.

11 Jul 2023

New Study Shows How Roots Detect and React to Higher Temperatures

Plant roots have their own thermometer to measure the temperature of the soil around them and they adjust their growth accordingly.

11 Jul 2023

Research may Offer a New Way to Break Through Cancer's Hypoxia-Induced Defenses

For most of our tissues and cells, a lack of oxygen, or hypoxia, is bad news. Cancer cells, on the other hand, can thrive in these hypoxic conditions, which render tumors less susceptible to anti-cancer treatments, including radiation.

11 Jul 2023

Scientists Reveal How Honey Bees' Brains Work

Honey bees have to balance effort, risk and reward, making rapid and accurate assessments of which flowers are mostly likely to offer food for their hive.

11 Jul 2023

Global Cooling Caused Diversity of Species in Orchids, Confirms Study

Research led by the Milner Centre for Evolution at the University of Bath looking at the evolution of terrestrial orchid species has found that global cooling of the climate appears to be the major driving factor in their diversity.

11 Jul 2023

New Insight Into the Physiology of NO-Reducing Microorganisms

Nitric oxide (NO) is a central molecule in the global cycling of nitrogen, and also toxic. Little is known about if and how microbes can use NO as a substrate for growth.

11 Jul 2023

Scientists Use Synthetic Biology to Develop Underwater Adhesives

For more than half a century, scientists have been studying mussel foot proteins and how to synthetically duplicate their natural strength.

11 Jul 2023

Study Highlights Potential Causes for Changing Foraging Habits of Bumblebees

A new study highlights potential causes for changing foraging habits of bumblebees. Using advanced molecular techniques called pollen metabarcoding, researchers investigated interactions between bumblebees and plants in Cuxhaven, Germany, and how they changed over 60 years.

11 Jul 2023