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New spatial mapping method pinpoints new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

9 Jul 2020

Bacteria-induced cell fusion provokes the immune system and causes host cell destruction

Burkholderia pseudomallei is a bacterium in the soil that causes melioidosis, a tropical disease with high morbidity and mortality.

9 Jul 2020

Super-resolution microscopy methods reveal the smallest cell structures

Theoretically, high-resolution microscopy should make it possible to capture cell structures that have a resolution of a few nanometers.

8 Jul 2020

Study shows engineered natural killer immune cells can directly kill tumor cells

According to a study, researchers have successfully designed natural killer immune cells that destroy head and neck tumor cells in mice.

8 Jul 2020

Newly synthesized peptides show promise for treating gastrointestinal disorders

Thanks to the interesting group of trefoil factor peptides, both industry and research could usher in better treatments for chronic disorders.

8 Jul 2020

SOAT1 enzyme offers a promising therapeutic target for pancreatic cancer

Researchers from CSHL have discovered that the growth of pancreatic cancer cells can be stopped by disrupting the way cholesterol is stored by the cells.

8 Jul 2020

Rapid COVID-19 diagnostic infection testing

Porvair Sciences reports on the Vyon porous plastic filters it is supplying to University of Cambridge spinout company - Diagnostics for the Real World for their game-changing SAMBA II machine that provides diagnosis of COVID-19 infection in under 90 minutes.

From Porvair Sciences Limited 8 Jul 2020

Study highlights lesser-known options to tackle climate change, food security and land degradation

How can some of world's biggest problems - climate change, food security and land degradation - be tackled simultaneously?

From Rutgers University 8 Jul 2020

Integrating metabolomics and genomics to improve patient diagnosis

A patient and family walk into a doctor's office. They hope that the latest tests will reveal what is causing the patient's illness and end the diagnostic odyssey they have been going through for years.

8 Jul 2020

Scientists discover role of surface diffusion in protein transport

Many of the most promising medicines under development are proteins, often antibodies, to help patients fight disease. These proteins must be purified as part of the manufacturing process -- a task that can be tricky and result in costly waste.

8 Jul 2020

Protein PRC1 acts as a 'viscous glue' during cell division, research shows

An over-abundance of the protein PRC1, which is essential to cell division, is a telltale sign in many cancer types, including prostate, ovarian, and breast cancer.

8 Jul 2020

Salk researchers discover genetic 'dial' to fine-tune the immune response

The human immune system is a finely-tuned machine, balancing when to release a cellular army to deal with pathogens, with when to rein in that army, stopping an onslaught from attacking the body itself.

8 Jul 2020

Researchers map non-coding, 'functional' genome in maize during early development

Growth and development of all organisms depends on coordinated regulation of gene expression in time and space, and this is largely controlled by non-coding sequences in the genome.

8 Jul 2020

Animal proteins more effective than plant proteins in building aging muscles

On a gram for gram basis, animal proteins are more effective than plant proteins in supporting the maintenance of skeletal muscle mass with advancing age, shows research presented this week at The Physiological Society's virtual early career conference Future Physiology 2020.

8 Jul 2020