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Exploring the Potential of Bacteriophages

Bacteriophages, viruses that target and destroy bacteria, are ubiquitous in the natural world. They play a crucial role in controlling microbe populations, though the mechanisms behind this regulation are not yet fully understood.

14 Jun 2024

New Platform Enables Ultra-Detailed Imaging of Human Brain Tissue

Researchers reveal that a novel technology allows for the simultaneous capture at many scales of neuronal projection, synapse distribution, cellular architecture, and protein expression in large-scale human brain tissues.

14 Jun 2024

First Evidence of Oocyte Cohesion Rejuvenation Discovered in Fruit Flies

A Dartmouth study conducted on fruit flies reports the first evidence in any organism that oocytes-;the cells that become eggs-;regularly rejuvenate the critical protein linkages that bind chromosomes together.

13 Jun 2024

Germ Cells Found to Drive Sex-Dependent Lifespan Differences in Vertebrates

Women live longer than men. This isn't unique to humans, either; we see this trend in a wide range of other animals. Biologists have theorized that the discrepancy in life expectancy between sexes might be partly related to reproduction, but how?

13 Jun 2024

Study Uncovers Link Between Genetic Variants and Mosaic Loss of X Chromosome in Aging Women

Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX.

13 Jun 2024

Progress in Ingestible Microbiome Sampling Pill Technology

At the Tufts University School of Engineering, significant progress has been made in creating a tiny device that is comparable in size to a vitamin pill and can be swallowed to sample the entire population of microorganisms in a person's gastrointestinal tract.

13 Jun 2024

Human Antibodies Offer Hope for Improved Black Widow Antivenom

Sera produced from horses can be used to treat serious illnesses caused by black widow bites. But this approach is not totally secure. To address this, scientists have produced entirely human antibodies that are capable of neutralizing the European black widow's alpha-latrotoxin.

13 Jun 2024

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Whether forcing adult cardiomyocytes to reverse from the oxidative phosphorylation phenotype to the glycolysis phenotype would also restore their mitotic ability.

13 Jun 2024

New Study Reveals Microbial Role in Soil Carbon Emissions

When soil microbes eat plant matter, the digested food follows one of two pathways. Either the microbe uses the food to build its own body, or it respires its meal as carbon dioxide (CO2) into the atmosphere.

12 Jun 2024

Ancient Archaea Reveal Secrets of Hydrogen Utilization

An international scientific team has redefined our understanding of archaea, a microbial ancestor to humans from two billion years ago, by showing how they use hydrogen gas.

12 Jun 2024

Virus-Like Nanoparticles Facilitate DNA Release and Host Reproduction in Streptomyces

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

12 Jun 2024

Simplified Proteomics Method Could Open the Door Toward Precision Medicine

Proteins are workhorses that carry out most of the biological functions in our cells.

12 Jun 2024

Exploring the Use of Weakened Viruses for Cancer Treatment

Scientists at Northwestern Medicine have found that an attenuated virus can aid in the elimination of cancer in mice. Furthermore, mice given this virus treatment had a higher lifetime tumor-prevention rate.

12 Jun 2024

AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

Innovative ssREAD Database Provides Rich Alzheimer's Disease RNA-Seq Resources for Researchers

The Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease, or ssREAD.

12 Jun 2024

Shaping the Brain: Experience-Dependent Plasticity in Development, Learning and Memory

Explore the groundbreaking work of Mark Bear, a leading figure in neuroscience, as he shares insights on synaptic plasticity, learning, and the future of neurological research.

12 Jun 2024

SPT Labtech Brings the Power of Miniaturization to More Genomics Researchers with mosquito® Gen3

SPT Labtech, a global leader in the design, development and manufacture of automated instrumentation and consumables for life science applications, has expanded its nanoliter liquid handling portfolio with the launch of mosquito Gen3.

From SPT Labtech 12 Jun 2024

Super-Cooled Brain Cell Molecules Shed Light on Epilepsy Drug Action

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius -; nearly twice as cold as the coldest places in Antarctica -; scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

11 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

Discovery Speeds Up Cyclic Peptide Production for Antibiotic Development

A discovery made by scientists at King's College London could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.

11 Jun 2024