Malignant News and Research

RSS

Hydrogels based on modified pectins could be used for neural tissue restoration

Far Eastern Federal University (FEFU) scientists have developed implantable hydrogels based on plant polysaccharides (pectins). They can play the role of an artificial extracellular matrix, a special network of molecules that fills the space between body cells.

14 Aug 2020

Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Using a detailed genetic analysis, a research team from Japan-based Kumamoto University has discovered that the NSD2 enzyme, which controls the actions of several genes, also functions to block the aging of cells.

10 Aug 2020

Researchers use mathematical modeling to unravel the mechanisms behind tetraploidy

Cell division is a fundamental process that organisms need to reproduce, grow, and make repairs. But when an error disrupts this complex biological process, cellular abnormalities can lead to diseases, such as cancer, where cells are enabled to grow and divide out of control.

27 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

Study reveals key factor that influences malignant cells to develop into tumor

Researchers have unraveled a crucial factor that governs whether malignant cells will develop into a tumor. The study was recently published in the eLife journal.

22 Jul 2020

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

The Josep Carreras Leukaemia Research Institute, a public centre pertaining to the Generalitat de Catalunya's (Government of Catalonia) CERCA network, has created the OneChain Immunotherapeutics spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis.

21 Jul 2020

Scientists imitate the functioning of brain neurons using semiconductor materials

Especially activities in the field of artificial intelligence, like teaching robots to walk or precise automatic image recognition, demand ever more powerful, yet at the same time more economical computer chips.

15 Jul 2020

Golgi membrane protein drives growth and invasion of breast cancer

The cover for issue 28 of Oncotarget features Figure 5, "TMEM165 expression levels alters N-linked glycosylation," by Murali, et al., and reported that the TMEM165 protein was not detected in non-malignant matched breast tissues and was detected in invasive ductal breast carcinoma tissues by mass spectrometry.

15 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

Human papilloma viruses may play a causal role in prostate cancer

Human papilloma viruses (HPVs) - a common group of viruses known to cause cervical cancers - may also have a causal role in prostate cancer, according to a literature review published in the open access journal Infectious Agents and Cancer, supporting the case for universal HPV vaccination.

14 Jul 2020

Study shows how inflammatory changes in tumors cause drug resistance in blood vessels

Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in the poor prognosis of cancer patients.

2 Jul 2020

Pseudotargeted metabolomics method can help analyze bile and amino acids

A team of researchers has come up with a procedure through which the pseudotargeted metabolomics technique can be systematically summarized and upgraded.

29 Jun 2020

Researchers identify genetic variants that predispose to cancer

The concept that cancer development is “monitored and prevented” by the immune system was first suggested at the beginning of the previous century.

26 Jun 2020

CAR T Cell Therapy: Potential For Considerable Savings

CAR T cell therapy is a new and, in some cases, highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system.

24 Jun 2020

Developments in Engineered T Cells for Type 1 Diabetes

AZoLifeSciences speaks to Professor David J. Rawlings from the Seattle children's hospital about recent developments in engineered T cells for type 1 diabetes.

23 Jun 2020

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

From UC San Diego 12 Jun 2020

Malignant News and Research

Hydrogels based on modified pectins could be used for neural tissue restoration

Genetic analysis reveals the inhibitory role of NSD2 enzyme in cellular senescence

Researchers use mathematical modeling to unravel the mechanisms behind tetraploidy

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

Study reveals key factor that influences malignant cells to develop into tumor

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

Scientists imitate the functioning of brain neurons using semiconductor materials

Golgi membrane protein drives growth and invasion of breast cancer

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

PET radiotracer is safe and effective for imaging malignant brain tumors

Human papilloma viruses may play a causal role in prostate cancer

Study shows how inflammatory changes in tumors cause drug resistance in blood vessels

Pseudotargeted metabolomics method can help analyze bile and amino acids

Researchers identify genetic variants that predispose to cancer

CAR T Cell Therapy: Potential For Considerable Savings

Developments in Engineered T Cells for Type 1 Diabetes

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Researchers identify genes involved in the development of malignant brain tumor

New technology to rapidly create antibody-drug conjugates

New technology can help map immune cells in different types of brain tumors

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics