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Scientists identify mechanism involved in new precision cancer drug for blood cancers

University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published today in Nature Communications.

23 Oct 2020

New collaboration to develop machine learning methods for chemical discovery

The discovery and formulation of new drugs, antivirals, antibiotics and in general chemicals with tailored properties is a long and painstaking process.

21 Oct 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

Scientists discover key parameters to better predict cancer-killing effect of neoantigens

Neoantigens, tiny markers that arise from cancer mutations, flag cells as cancerous and could be the key to unlocking a new generation of immunotherapies.

14 Oct 2020

Immunomodulatory and antioxidant feed additives can reduce effects of coccidiosis

Broiler chicken producers the world over are all too familiar with coccidiosis, a parasite-borne intestinal disease that stalls growth and winnows flocks.

8 Oct 2020

80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health.

5 Oct 2020

New project to advance technologies for carbon capture through catalysis

Climate-conscious consumers often take steps to curb their emissions of greenhouse gases. For example, you might drive a hybrid car to reduce your use of fossil fuels, which release carbon dioxide into the atmosphere during combustion.

1 Oct 2020

Study may help develop new immunotherapies for different types of tumors

A team of researchers have plotted the genes that enable cancer cells to avoid being destroyed by the immune system.

From University of Toronto 25 Sep 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Chemists build artificial cells that can communicate with natural living cells

New research by an international team of chemists describes a new type of artificial cell that can communicate with other cells within the body--with potential applications in the field of smart pharmaceuticals.

23 Sep 2020

Researchers aim to convert greenhouse gas emissions into fuels

Shaama Sharada calls carbon dioxide -- the worst offender of global warming -- a very stable, "very happy molecule."

2 Sep 2020

Study identifies precise rules for the disposition of CTCF proteins

The 3D structure of DNA is typically established by a sequence of spacial rules on the basis of specific protein sequences and their order.

28 Aug 2020

Study sheds light on the function of ribosome binding sites

Genome sequencing of plants, bacteria, and even human beings has turned out to be a standard process, but despite this fact, the genome continues to raise several unanswered questions.

28 Aug 2020

New technique could accelerate drug research for various diseases

Alicyclic compounds are groups of organic chemical compounds that have led to the development of a number of medications.

19 Aug 2020

COVID-19 Prevention Network announces two trials to evaluate monoclonal antibodies

The COVID-19 Prevention Network (CoVPN) today announced two Phase 3 trials to determine whether monoclonal antibodies (mAbs) can prevent SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2020

Study indicates a powerful treatment for pulmonary fibrosis

A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF).

7 Aug 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

From The University of California, Davis 21 Jul 2020