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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Fighting Drug-Resistant TB with a Novel Antibiotic

A novel semi-synthetic molecule that produces significant activity against strains of Mycobacterium tuberculosis, including those that are resistant to drugs, can be generated from natural compounds according to a study published in the American Society for Microbiology journal Microbiology Spectrum.

4 Oct 2024

Zinc Inhibits Plasmid Transfer in Gut Microbes

Genes responsible for antimicrobial resistance (AMR) can spread from microbe to microbe through circular genetic material called plasmids, and this lateral transfer occurs in the gut. This week in Applied and Environmental Microbiology, researchers in Iowa report that the transmission of some AMR plasmids may be inhibited by a readily available source-;dietary zinc supplements.

4 Oct 2024

Scientists Successfully Map the Entire Fruit Fly Brain

A team of scientists supported by the National Institutes of Health (NIH)'s The BRAIN Initiative, including Davi Bock, Ph.D., Associate Professor of Neurological Sciences at UVM's Robert Larner, M.D. College of Medicine, recently made a substantial advancement in neurobiological research by successfully mapping the entire brain of Drosophila melanogaster, more commonly known as the fruit fly.

3 Oct 2024

Stem Cell Study Reveals Developmental Dance Behind Individual Variation

Researchers at the Johns Hopkins University School of Medicine have conducted a comprehensive analysis of the variations present in human stem cells. This study sheds light on how the unique “developmental dance” at the molecular level within an individual's cells can shape the formation of the brain and the body.

26 Sep 2024

Human Urine Recycling Promotes Agricultural Sustainability

Bacterial communities in soil are as resilient to human urine as synthetic fertilizers – making recycling the bodily fluid as a fertilizer for agricultural crops a viable proposition, according to a new study.

24 Sep 2024

Unveiling the Molecular Mechanisms of Shigella flexneri Infection

Virginia Tech researchers have learned how bacteria manipulate molecules to infect the host organism.

23 Sep 2024

Antifreeze Fish Shed Light on How New Genes Evolve

From where do novel genes originate? In a recent study, a group of University of Arkansas researchers studying biological sciences set out to address that topic.

20 Sep 2024

New Guidelines Enhance Accuracy of DNA-Protein Interaction Studies

Researchers at University of California San Diego have published new guidelines that could help scientists significantly improve their results when quantifying the interactions between DNA and proteins.

17 Sep 2024

New Guidelines for Accurate Spike-In Normalization in DNA-Protein Interaction Studies

New criteria developed by researchers at the University of California San Diego may greatly enhance the accuracy of results obtained by scientists when assessing the interactions between proteins and DNA.

16 Sep 2024

Soil pH Influences Microbial Community Formation and Nitrogen Cycling

Though a founding concept of ecology suggests that the physical environment determines where organisms can survive, modern scientists have suspected there is more to the story of how microbial communities form in the soil.

15 Sep 2024

CRISPR and Antibodies Offer New Hope for Improving CAR-T Cell Therapy Outcomes

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

13 Sep 2024

Monoclonal Antibody SC27 Shows Broad Effectiveness Against SARS-CoV-2 Variants

A monoclonal antibody appears effective at neutralizing the numerous variants of SARS-CoV-2, as well as related viruses in animals that could pose a threat if they were to begin spreading in people.

10 Sep 2024

Study Reveals How Surface Properties Affect Bacterial Motility

As bacteria continue to become more resistant to antibiotics, it will be harder to treat bacterial infections, leading to more severe illnesses, longer hospital stays, and higher mortality rates.

10 Sep 2024

Common Skin Fungus Identified as a Potential Factor in Tumor Growth

A common skin fungus, Malassezia globosa may invade deep tissues through the skin or by other means, then cause tumor growth, according to a new study.

6 Sep 2024

Innovative Computational Tool Analyzes Gut Microbiome for Early Health Insights

A team of Mayo Clinic researchers has developed a unique computational tool that analyzes the gut microbiome, a complex ecosystem of trillions of bacteria, fungi, viruses, and other microorganisms within the digestive system, to provide insights about general well-being.

5 Sep 2024

Climate Change Exacerbates Valley Fever Threat

A fungal disease called valley fever is on the rise in the western United States. It typically manifests as flu-like symptoms, but it can potentially have fatal or extremely serious side effects.

4 Sep 2024

European Commission Approves Erdafitinib for Advanced Urothelial Carcinoma

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved BALVERSA®▼(erdafitinib) as a once-daily oral monotherapy for the treatment of adult patients with unresectable or metastatic urothelial carcinoma (mUC), harbouring susceptible fibroblast growth factor receptor 3 (FGFR3) genetic alterations who have previously received at least one line of therapy containing a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor in the unresectable or metastatic treatment setting.

30 Aug 2024

RYBREVANT Receives EC Nod for Advanced Lung Cancer Treatment

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved a Type II extension of indication for RYBREVANT®▼ (amivantamab) in combination with chemotherapy (carboplatin and pemetrexed), for the treatment of adults with advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) Exon 19 deletions (ex19del) or Exon 21 L858R substitution (L858R) mutations, after failure of prior therapy including an EGFR tyrosine kinase inhibitor (TKI).

30 Aug 2024

Transforming Waste into Culinary Delights with Neurospora

Chef-turned-chemist Vayu Hill-Maini has a passion: to turn food waste into culinary treats using fungi.

30 Aug 2024

Evolution of Blood Sugar Regulation in Neotropical Bats

Humans must regulate blood sugar concentrations to stay healthy and to fuel our cells. Too little or too much can cause serious health complications, and high blood sugar is a hallmark of the metabolic condition, diabetes. New research from the Stowers Institute for Medical Research may enable potential solutions to metabolic disease by turning to evolution and to bats.

29 Aug 2024