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Study Reveals Limits of Epigenetic Clocks in Predicting Biological Age

Epigenetic clocks show varying accuracy across tissues, underscoring the need for tissue-specific calibration in biological age assessments and health research.

13 Feb 2025

Scientists Discover Hidden Role of RNA Introns in Cellular Stress Response

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to oxidative stress.

12 Feb 2025

Mismatch Repair Genes Found to be Key Drivers of Huntington's Disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

12 Feb 2025

Mitochondrial Transfer Uncovered as Key Player in Cancer Immune Evasion

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

12 Feb 2025

Synthetic Condensates Turbocharge Protein Production in Bacteria

Biomedical engineers at Duke University have developed a novel synthetic method that enhances bacteria's ability to produce higher quantities of specific proteins, including those that would typically harm them, such as antibiotics.

12 Feb 2025

Mutant Vimentin Promotes Aggressive Breast Cancer Growth

Vimentin is a type III intermediate filament (IF) protein typically expressed in cells that differentiate into connective tissue, blood vessels, and lymphatic tissue (mesenchymal cells).

12 Feb 2025

Single-Cell Analysis Reveals Critical Kidney Cell Types Involved in Disease

Researchers at the University of Pennsylvania's Perelman School of Medicine have published a new study in the journal Science that suggests over 1,000 genes could be potential targets for kidney disease treatment.

12 Feb 2025

Researchers Uncover Genomic Drivers Behind Aggressive Breast Cancer

Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the patient will experience a recurrence years after their initial diagnosis.

11 Feb 2025

Researchers Cultivate an Ultrasmall Bacterial Strain Parasitizing Archaea

AIST researchers, in collaboration with JAMSTEC, Hokkaido University and Tohoku University, have succeeded in cultivating an ultrasmall bacterial strain parasitizing archaea and classified the strain PMX.108T as new species and genus of Minisyncoccus archaeiphilus.

11 Feb 2025

Study Reveals How Gut Bacteria Influence Brain Protein Modifications

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease.

11 Feb 2025

Study Uncovers Immune Cell Interaction Driving Aggressive Brain Tumor Growth

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine.

11 Feb 2025

New Study Explains Why Flu Virus Forms Filaments

Influenza A virus particles strategically modify their shape becoming either spheres or larger filaments to enhance their ability to infect cells based on environmental conditions, according to a new study conducted by scientists at the National Institutes of Health (NIH).

11 Feb 2025

New Study Reveals Energy-Saving Strategies in Neuronal Protein Synthesis

Nerve cells use incredible energy-saving techniques while still carrying out their primary functions.

10 Feb 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

Cryo-EM Uncovers Hidden Complexity in Collagen Structure

The most prevalent protein in the body, collagen, has long been thought to be a predictable structural element of tissues.

10 Feb 2025

Uncovering a New Mechanism in Immune Cell Regulation During Parasitic Infections

Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune response against parasites.

10 Feb 2025

Protecting Plant Cells from Damage with ATG8ylation

Plants droop and shed their leaves when parched, but with a splash of water, their stems regain strength and their leaves unfurl.

10 Feb 2025

Research Reveals Key Mitochondrial Role in Social Recognition Memory

Virginia Tech neuroscientists have uncovered a mitochondrial process that supports the brain cells critical for learning, memory, and social recognition.

10 Feb 2025

BioMed X and Merck Partnership Makes Significant Strides in Understanding ecDNA Biology

German independent research institute BioMed X announces the successful completion of its oncology research project in partnership with Merck. The data generated by this project has been acquired by Merck for further development, potentially leading to new therapeutic approaches in precision oncology.

10 Feb 2025