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Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

In a new study, Yale Cancer Center researchers have defined the genetic landscape of uterine leiomyosarcomas (uLMS).

6 Apr 2021

Researchers use single-cell RNA sequencing to study the development of leaves

How do we become a complex, integrated multicellular organism from a single cell? While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

6 Apr 2021

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

In the fight against cancers, activating mutations in the RAS family of genes stand in the way of finding viable treatment options.

6 Apr 2021

High expression of cell death genes linked to increased risk of dying early from lung cancer

Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.

6 Apr 2021

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

A pre-clinical study for melanoma and neuroblastoma shows that a customized tumor cell vaccine technique that targets Myc oncogenes coupled with checkpoint therapy produces an active immune response that bypasses antigen selection and immune privilege.

5 Apr 2021

New mechanism of transcriptional regulators influences tumor development

The Wistar Institute scientists have discovered a novel mechanism of transcriptional regulation of cellular senescence that promotes the release of inflammatory molecules that, in turn, affect tumor growth by changing the surrounding microenvironment.

2 Apr 2021

New research aims to take the study of the human genome to the next level

A global consortium of biologists, geneticists, mathematicians, clinicians, and other scientists is all set to elevate the study of the human genome to the next level—developing an exhaustive atlas of genetic variants to improve the understanding, diagnosis, and treatment of disease.

2 Apr 2021

Discovering a new genetic mutation in Schizophrenia

A new genetic mutation has been discovered in schizophrenia, and we spoke to Dr. Todd Lencz from the Feinstein Institutes for Medical Research to find out more.

From Northwell Health 1 Apr 2021

Six novel CRISPR-Cas12a variants expand genome engineering in plants

Yiping Qi continues to create new genome editing and engineering in plants, with the ultimate objective of enhancing the efficiency of food production.

31 Mar 2021

Developing a new CRISPR technique

Researchers from Vanderbilt University spoke to AZoLifeSciences about a new CRISPR technique that could help us to further understand the mechanisms behind cancer.

From Vanderbilt University 31 Mar 2021

Study reveals molecular mechanisms involved in eliminating unwanted cells in the body

Researchers have uncovered molecular mechanisms involved in removing unwanted cells in the body.

29 Mar 2021

Strong cell-cell junctions preserve the quiescent properties of stem cells

The skin is known to be the largest organ in the human body, and its outermost layer, called the epidermis, is renewed every three weeks.

29 Mar 2021

Study reveals molecular mechanisms involved in the maintenance of naïve embryonic stem cells

Researchers have explained mechanisms that play a role in maintaining the embryonic stem cells in the most optimized state for use in regenerative medicine.

26 Mar 2021

Specific genes play key roles in response to water stress across bioenergy grass species

The Miscanthus genus of grasses, commonly used to add movement and texture to gardens, could quickly become the first choice for biofuel production. A new study shows these grasses can be grown in lower agricultural grade conditions - such as marginal land - due to their remarkable resilience and photosynthetic capacity at low temperatures.

26 Mar 2021

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

A multi-institutional collaboration has revealed that α-solanine, a toxic compound found in potato plants, is a divergent of the bitter-tasting α-tomatine, which is found in tomato plants.

26 Mar 2021

Scientists generate a detailed molecular atlas of lung development

Researchers at the Perelman School of Medicine at the University of Pennsylvania have produced a detailed molecular atlas of lung development, which is expected to be a fundamental reference in future studies of mammalian biology and of new treatments for diseases, such as COVID-19, that affect the lungs.

25 Mar 2021

Gender difference accounts for major psychiatric disorders

According to an analysis of sex variations in the genetics of bipolar disorder, schizophrenia, and major depressive disorders.

24 Mar 2021

Specific enzyme can delay the growth and spread of neck and head carcinomas

Scientists were able to considerably delay the growth and proliferation of tumors in mice and improve the effectiveness of immunotherapy.

24 Mar 2021

Stem cell therapy could help restore debilitating muscle loss that happens with age

As the name implies, induced pluripotent stem cells can become any type of cell in our body, and scientists have evidence that when they prompt them to become muscle progenitor cells they can help restore the sometimes debilitating muscle loss that happens with age.

24 Mar 2021

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

Researchers have used an upgraded version of the gene-editing tool, CRISPR/Cas9, to knock out up to 12 genes in plants in just one go.

23 Mar 2021

Genes News and Research

Study identifies multiple genes that are frequently mutated in uterine leiomyosarcomas

Researchers use single-cell RNA sequencing to study the development of leaves

Novel cell-to-cell communication network helps cancers regrow following genotoxic therapies

High expression of cell death genes linked to increased risk of dying early from lung cancer

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

New mechanism of transcriptional regulators influences tumor development

New research aims to take the study of the human genome to the next level

Discovering a new genetic mutation in Schizophrenia

Six novel CRISPR-Cas12a variants expand genome engineering in plants

Developing a new CRISPR technique

Study reveals molecular mechanisms involved in eliminating unwanted cells in the body

Strong cell-cell junctions preserve the quiescent properties of stem cells

Study reveals molecular mechanisms involved in the maintenance of naïve embryonic stem cells

Specific genes play key roles in response to water stress across bioenergy grass species

Toxin in potatoes is a divergent of bitter-tasting compound in tomatoes

Scientists generate a detailed molecular atlas of lung development

Gender difference accounts for major psychiatric disorders

Specific enzyme can delay the growth and spread of neck and head carcinomas

Stem cell therapy could help restore debilitating muscle loss that happens with age

Improved version of CRISPR/Cas9 tool helps study the interaction of various genes

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