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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Singapore researchers discover protein that drives cancer progression

Cancers arise when the genetic code of normal cells is altered, causing excessive growth. Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have discovered a protein that drives the growth of cancers of the esophagus or liver by altering the genetic code in a novel way.

30 Jun 2020

Genome sequencing reveals signposts in DNA for cancer, disease risk

By sequencing entire genomes for DNA modifications, and analyzing both cancer tissues and healthy ones, Hackensack Meridian Health researchers and doctors have found what could be a key to risks for cancer and other diseases: specific locations in the DNA where those expression changes (methylation) are imbalanced, according to a new publication.

30 Jun 2020

Deep-learning-based computational models predict the activities of SpCas9 variants

Specific sequences of DNA are typically cut using CRISPR-Cas9 that has become one of the most effective and convenient biotechnology tools today.

29 Jun 2020

MRI Scan Used For Heart Disease Could Also Pick Out Aggressive Cancers

An MRI scan used for heart disease could help assess whether children's cancers are especially aggressive and spot early signs that treatments are working.

29 Jun 2020

Function-Based Sequencing Technique Permits Analysis Of Just A Single Bacteria Cell

A function-based sequencing technique using optical tweezers and taking advantage of the properties of gravity is letting researchers analyze bacteria cells.

29 Jun 2020

Researchers identify novel protein complex that regulates chromosome segregation

Researchers from the University of Tsukuba have identified a novel protein complex that regulates Aurora B localization to ensure that chromosomes are correctly separated during cell division.

26 Jun 2020

Researchers identify genetic variants that predispose to cancer

The concept that cancer development is “monitored and prevented” by the immune system was first suggested at the beginning of the previous century.

26 Jun 2020

Single-cell sequencing can reveal genetic diversity of cancer cells

In the past, the potential to sequence the genome of the tumor has redefined the treatment of cancer by detecting cancer drivers at the molecular level.

26 Jun 2020

Helping to unravel the genetic diversity of cancer tumors

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the years by identifying drivers of cancer at the molecular level.

26 Jun 2020

Genome study opens pathway toward sustainable edible seaweed

Since the 1980s, in seaweed farms dotted along the coastline of the subtropical islands of Okinawa, farmers have cultivated the edible brown alga.

26 Jun 2020

Researchers perform room-temperature X-ray measurements on SARS-CoV-2 main protease

A team of researchers at the Department of Energy's Oak Ridge and Argonne national laboratories has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease -- the enzyme that enables the virus to reproduce.

26 Jun 2020

Super-resolution technology helps visualize DNA replication in single human cells

DNA replication is a process of critical importance to the cell, and must be coordinated precisely to ensure that genomic information is duplicated once and only once during each cell cycle.

26 Jun 2020

New approach spurs production of antibiotic or antiparasitic compounds in bacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

26 Jun 2020