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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

A preclinical study led by scientists at Sanford Burnham Prebys has established that AAV8-TNAP-D10--a gene therapy that replaces a key enzyme found in bone--may be a safe and effective single-dose treatment for hypophosphatasia (HPP).

8 Jun 2021

Harmful DNA mutations play a key role in the conservation of threatened species

Researchers in Lund, Copenhagen, and Norwich have demonstrated that detrimental mutations in DNA play a vital—but often overlooked—role in vulnerable species translocation and conservation initiatives.

8 Jun 2021

New insights on how synovial sarcoma develops and spreads

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

7 Jun 2021

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

4 Jun 2021

Study describes the impact of DNA methylation on the 3D structure of genome

Although all cells in an organism share the same DNA sequence, their shapes, roles, and even lifespans differ drastically.

4 Jun 2021

Novel protein could improve treatment outcomes after heart attacks

New research, headed by scientists from Washington State University, has revealed a protein that could be crucial for enhancing treatments after a heart attack.

4 Jun 2021

Scientists design new gene drive to stop the transmission of devastating diseases

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever.

From UC San Diego 3 Jun 2021

New method can help diagnose unsolved cases of rare diseases across Europe

Experts in rare diseases have recently described the results of a collaboration to diagnose individuals living with unsolved cases of rare disorders throughout Europe.

3 Jun 2021

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a mechanism that allows them to recover their initial water volume and avoid dying.

2 Jun 2021

Understanding molecular determinants of liver cancer in patients with Indigenous American ancestry

Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry" which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood.

2 Jun 2021

Life expectancy can be increased by an average of 30% in transgenic mice, study shows

Aging is associated with an overall decline in health and increased frailty, and is a major risk factor for multiple chronic diseases.

2 Jun 2021

A gene that impacts the development of bone cancer in children discovered

Researchers have discovered a gene, OTUD7A, that impacts the development of Ewing sarcoma, a bone cancer that occurs mainly in children.

2 Jun 2021

Diet plays a crucial role in liver disease outcome, mouse model shows

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD patients are at higher risk of developing Non-alcoholic steatohepatitis (NASH), which causes severe and chronic liver inflammation, fibrosis and liver damage.

2 Jun 2021

Each city has its own exclusive microbiome, finds study

A new study performed by researchers report that each city has its own exclusive microbiome or a “fingerprint” of bacteria and viruses that uniquely identify it.

1 Jun 2021

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

Scientists describe pathway that leads to accelerated flowering of plants in low-nitrogen soils

Scientists from Japan, Europe and the USA have described a pathway leading to the accelerated flowering of plants in low-nitrogen soils. These findings could eventually lead to increases in agricultural production.

31 May 2021

Genetic editing tools stop the spread of Culex mosquitoes

Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases.

From UC San Diego 31 May 2021

Gene News and Research

Further Reading

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

Harmful DNA mutations play a key role in the conservation of threatened species

New insights on how synovial sarcoma develops and spreads

Some Type 2 diabetes patients could benefit from bone marrow stem cell transplants, study shows

Study describes the impact of DNA methylation on the 3D structure of genome

Novel protein could improve treatment outcomes after heart attacks

Scientists design new gene drive to stop the transmission of devastating diseases

New method can help diagnose unsolved cases of rare diseases across Europe

Scientists discover the central role of LRRC8A gene in cellular ability to survive osmotic shock

Understanding molecular determinants of liver cancer in patients with Indigenous American ancestry

Life expectancy can be increased by an average of 30% in transgenic mice, study shows

A gene that impacts the development of bone cancer in children discovered

Diet plays a crucial role in liver disease outcome, mouse model shows

Each city has its own exclusive microbiome, finds study

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

Scientists describe pathway that leads to accelerated flowering of plants in low-nitrogen soils

Genetic editing tools stop the spread of Culex mosquitoes

Scientists identify mechanism by which head and neck cancer cells subvert adjacent normal tissue

Non-specific lipid transfer proteins help improve wheat tolerance

Study reveals how cells respond to changes in the mechanical microenvironment

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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