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Genetic editing tools stop the spread of Culex mosquitoes

Since the onset of the CRISPR genetic editing revolution, scientists have been working to leverage the technology in the development of gene drives that target pathogen-spreading mosquitoes such as Anopheles and Aedes species, which spread malaria, dengue and other life-threatening diseases.

From UC San Diego 31 May 2021

More informed choices of contraceptives can prevent breast cancer

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

31 May 2021

Novel drug is highly effective in preventing severe COVID-19 in mice

The drug diABZI -- which activates the body's innate immune response -- was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2,

31 May 2021

Scientists identify mechanism by which head and neck cancer cells subvert adjacent normal tissue

Up to half of patients with head and neck squamous cell carcinoma will experience tumor recurrence or new tumors--tumors that often spread and are difficult to treat.

28 May 2021

Non-specific lipid transfer proteins help improve wheat tolerance

Fusarium Head Blight (FHB), often called scab, is a serious disease of small grain cereals like barley and wheat that affects farmers worldwide.

27 May 2021

Researchers discover new genes and functionalities in bovine genome

Modern genetic research often works with what are known as reference genomes. Such a genome comprises data from DNA sequences that scientists have assembled as a representative example of the genetic makeup of a species.

27 May 2021

Genomic study can reveal adaptive mechanisms of life under future ocean acidification

Human-driven global change is challenging the scientific community to understand how marine species might adapt to predicted environmental conditions in the near-future (e.g. hypoxia, ocean warming, and ocean acidification).

27 May 2021

New software tool detects, evaluates, and quantifies off-target editing activity

CRISPR technology enables researchers to edit genomes by modifying DNA sequences and hence gene function.

27 May 2021

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

The chemotherapy drug decitabine is commonly used to treat patients with blood cancers, but its response rate is somewhat low. Researchers have now identified why this is the case, opening the door to more personalized cancer therapies for those with these types of cancers, and perhaps further afield.

25 May 2021

Study could help develop peptide siRNA carrier for human oral cancer

MUSC Hollings Cancer Center researchers are exploring the use of peptide carriers for the delivery of small RNA drugs as a novel treatment for cancer. The team's recent work, published online March 19 in the Molecular Therapy - Nucleic Acids journal, lays the foundation for developing a clinically relevant peptide carrier RNAi-based drug treatment strategy for human oral cancer.

25 May 2021

Exposure to chemicals in plastic during the fetal stage is linked with a lower IQ

Bisphenol F chemical (found in plastics) may cause changes in a gene that is crucial for neurological development. Researchers from the Swedish universities of Uppsala and Karlstad made this discovery.

21 May 2021

Study shows how mitochondrial function impacts schizophrenia in patients with genetic disorder

Researchers have demonstrated how cell “batteries” play a significant role in whether patients with the chromosomal deletion syndrome acquire schizophrenia.

20 May 2021

Study identifies predictive causal role for specific cell types in type 1 diabetes

Researchers revealed a predicted causative role for certain cell types in type 1 diabetes by examining its genetic foundations.

From UC San Diego 20 May 2021

Study shows that Bubonic Plague had a long-term impact on immune gene expression

A new study shows that the Bubonic Plague has had a long-term impact on immune gene expression.

20 May 2021

Study identifies DNA alterations that underpin brain and cognitive decline in the elderly

According to a new mathematical model published recently in eLife, Alzheimer’s disease has some important similarities with healthy aging.

20 May 2021

Wild relatives of modern peanut plants can withstand diseases

The wild relatives of modern peanut plants have the ability to withstand disease in ways that peanut plants can't. The genetic diversity of these wild relatives means that they can shrug off the diseases that kill farmers' peanut crops, but they also produce tiny nuts that are difficult to harvest because they burrow deep in the soil.

From University of Georgia 19 May 2021

Genes News and Research

Genetic editing tools stop the spread of Culex mosquitoes

More informed choices of contraceptives can prevent breast cancer

Novel drug is highly effective in preventing severe COVID-19 in mice

Scientists identify mechanism by which head and neck cancer cells subvert adjacent normal tissue

Non-specific lipid transfer proteins help improve wheat tolerance

Researchers discover new genes and functionalities in bovine genome

Genomic study can reveal adaptive mechanisms of life under future ocean acidification

New software tool detects, evaluates, and quantifies off-target editing activity

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

Study could help develop peptide siRNA carrier for human oral cancer

Exposure to chemicals in plastic during the fetal stage is linked with a lower IQ

Study shows how mitochondrial function impacts schizophrenia in patients with genetic disorder

Study identifies predictive causal role for specific cell types in type 1 diabetes

Study shows that Bubonic Plague had a long-term impact on immune gene expression

Study identifies DNA alterations that underpin brain and cognitive decline in the elderly

Wild relatives of modern peanut plants can withstand diseases

Successful class of therapeutics attack and shut down unique and harmful genes

Exposure to even low levels of lead can trigger epigenetic changes

Study identifies new epigenetic control pathways in multiple myeloma growth

Study shows that inactivation of BRG1 leads to high genetic instability

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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