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New approach to determine the structure of large RNA molecules

Researchers have designed a new technique to establish the structures of huge RNA molecules at high resolution.

9 Oct 2020

Researchers identify specific neurons that may contribute to epileptic seizures

Epilepsy, results from impairment in brain cells and is often treated with drugs that counteract or control the seizures.

9 Oct 2020

Immune cell biomarker may help identify patients at risk for graft-versus-host disease

A recent report published in Science Translational Medicine by MUSC Hollings Cancer Center investigator Sophie Paczesny, M.D., Ph.D., sheds light on immune cell biomarkers that may reveal which patients are most at risk for graft-versus-host disease (GVHD), a life-threatening condition that can arise after hematopoietic stem cell transplantation (HSCT) for treatment of liquid cancers such as leukemia.

8 Oct 2020

Risk for melanoma could be estimated by DNA mutation count

Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UC San Francisco scientist who led a new study to detect DNA mutations in individual skin cells.

8 Oct 2020

Researchers demonstrate mysterious molecular concept for targeted drug delivery

Researchers have demonstrated a type of cellular binding that could lead to highly targeted treatments against diseases like cancer.

8 Oct 2020

New algorithm sharpens focus of world's most powerful microscopes

We have all seen in a TV show where a detective is reviewing grainy security footage, spots a person of interest, and asks a technician to "enhance that."

8 Oct 2020

Study confirms genetic link in cerebral palsy

A research team has found further evidence that rare gene mutations can cause cerebral palsy, findings which could lead to earlier diagnosis.

8 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Dried plum diet prevents bone loss associated with spinal cord injury

Findings from a new study among mice show a diet high in dried plum (prunes) completely prevents bone loss associated with spinal cord injury (SCI), while also restoring some of the bone lost following SCI.

7 Oct 2020

Scientists fine-tune plasma treatment to optimize plant growth and yield

Ever since scientists discovered that plasma treatment leads to faster growth and higher yields of some agricultural crops, physicists, chemists, and biologists have been working together to tease out the mechanisms driving this phenomenon.

7 Oct 2020

Maternal high sugar diet can impact developmental outcomes in infants

A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease. New research shows that when consumed by moms during the breastfeeding period, a high sugar diet can also impact developmental outcomes during infancy.

7 Oct 2020

New drug shows promise in the treatment of neuroblastoma

A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine.

7 Oct 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

High folic acid levels during pregnancy affect brain development of mouse embryos

A UC Davis MIND Institute study of pregnant mice found that high amounts of folic acid during pregnancy harmed the brain development of embryos.

From The University of California, Davis 6 Oct 2020

Researchers identify gene related to seed dispersal in green millet

For years, Elizabeth (Toby) Kellogg, PhD, member and Robert E. King Distinguished Investigator and other researchers at the Donald Danforth Plant Science Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them back to the lab.

6 Oct 2020

Cancer mutations occur in distinct patterns based on 3D structure of the genome

A new study from researchers at The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations.

6 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Vacuolar Tauopathy: New, rare genetic form of dementia discovered

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain -- which causes this newly discovered disease, as well as related neurodegenerative diseases like Alzheimer's Disease -- that could be targeted for new therapies. The study was published today in Science.

5 Oct 2020

Type and direction of force on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

5 Oct 2020

Researchers map genetic networks controlling human regulatory T cell identity

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

5 Oct 2020