Antigen News and Research

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Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

A treatment for multiple myeloma that harnesses the body's cancer-fighting T cells was safe in humans and showed preliminary signs of effectiveness, according to a clinical trial involving 23 patients with relapsed or treatment-resistant disease.

30 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Study shows neo-self antibody as major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

A novel technique to control and visualize functions of living cells

A research group composed of Professor Takayuki Shibata and his colleagues at Department of Mechanical Engineering, Toyohashi University of Technology has given greater functionalities to atomic force microscopy (AFM).

23 Jul 2020

Study shows how T cells become cancer-killing cells

Within the immune system, the T lymphocytes operate to kill cancer cells or infected cells.

21 Jul 2020

Modified mRNAs improve efficiency of protein synthesis

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired.

17 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

University of Alabama at Birmingham researchers have added fresh evidence that early exposure to vaccine-, bacterial- or microbiota-derived antigens has a dramatic effect on the diversity of antibodies an adult mammal will have to fight future infections by pathogens.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

Study confirms the efficacy of PSMA PET/CT in detection and management of recurrent prostate cancer

New research confirms the high impact of PSMA PET/CT in the detection and management of recurrent disease in prostate cancer patients.

14 Jul 2020

New technology generates immune response by delivering antigens to APCs in the spleen

Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

Fully automated chip can quickly and reliably determine patients’ blood type

Blood transfusion, if performed promptly, is a potentially life-saving intervention for someone losing a lot of blood. However, blood comes in several types, some of which are incompatible with others.

14 Jul 2020

Study shows engineered natural killer immune cells can directly kill tumor cells

According to a study, researchers have successfully designed natural killer immune cells that destroy head and neck tumor cells in mice.

8 Jul 2020

Study shows how epigenetics contribute to the development of autoimmune diseases

The human immune system is expected to guard people against the invasion of external microbes, but at times, it possibly leads to autoimmune disorders.

From Osaka University 6 Jul 2020

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

3 Jul 2020

CAR T Cell Therapy: Potential For Considerable Savings

CAR T cell therapy is a new and, in some cases, highly effective form of immunotherapy to treat certain types of cancer of the blood and lymph system.

24 Jun 2020

Antigen News and Research

Researchers develop CAR-T cell therapy based on TCR signal transduction

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

New approach is more effective in treating certain blood cancers

Study shows neo-self antibody as major cause of recurrent pregnancy loss

A novel technique to control and visualize functions of living cells

Study shows how T cells become cancer-killing cells

Modified mRNAs improve efficiency of protein synthesis

New, promising CAR T cell therapy results in exceptional patient recovery

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

Study confirms the efficacy of PSMA PET/CT in detection and management of recurrent prostate cancer

New technology generates immune response by delivering antigens to APCs in the spleen

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Fully automated chip can quickly and reliably determine patients’ blood type

Study shows engineered natural killer immune cells can directly kill tumor cells

Study shows how epigenetics contribute to the development of autoimmune diseases

Mineral-coated microparticles are better vehicles for promising mRNA-based therapy

CAR T Cell Therapy: Potential For Considerable Savings

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