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Study may lead to new therapeutic approaches against coronaviruses

The immune system secretes an endogenous protein that can strongly suppress coronaviruses, the pathogen that is responsible for causing the current pandemic.

29 Jul 2020

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

Movement of small RNAs underlies mobile RNA interference

Biologists have known for some time that RNA interference can silence genes in far-off cells. They suspected that a messenger substance “transmits” RNA interference.

29 Jul 2020

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Analyses of lung fluid cells from COVID-19 patients conducted on a supercomputer point to patterns that may explain the body's response to SARS-CoV-2.

29 Jul 2020

Scientists map the genome of aphid-like pest that decimates vineyards

Following a decade-long effort, scientists have mapped out the genome of an aphid-like pest capable of decimating vineyards. In so doing, they have discovered how it spreads -- and potentially how to stop it.

29 Jul 2020

Deep learning algorithm can infer molecular alterations in cancer from histology images

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

29 Jul 2020

Biologists identify a molecular mechanism that underlies phenotypic plasticity

Evolutionary and developmental biologist Craig Albertson and colleagues at the University of Massachusetts Amherst report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.

29 Jul 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

New technology helps visualize entire genome at molecular resolution

Scientists from Harvard University, CNAG, and CRG have demonstrated a pioneering technology that helps observe hundreds of genomes under the microscope.

29 Jul 2020

Study pinpoints the miRNA that promotes hair follicle growth

A research team from North Carolina State University has discovered a microRNA, or miRNA, that could make hairs to grow again.

29 Jul 2020

A novel approach to identify cancer targets using 'synthetic lethality'

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Artificial intelligence-based process can help design novel proteins

Proteins are known to perform complex tasks and catalyze chemical reactions, making them crucial for cell survival.

27 Jul 2020

Research identifies TLR7 gene that predisposes individuals to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

27 Jul 2020

Computational tool can help study APA mechanism that regulates gene expression

Scientists keen on solving the regulation of genes implicated in human health and disease are widening their horizons by closely APA.

27 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Deleting a key gene in mice in just their fat made tissues throughout these animals insulin resistant, in addition to other effects, a new study by UT Southwestern researchers shows.

24 Jul 2020

Epigenomic data can help characterize genes that play key role in cancer progression

As cancer cells evolve, many of their genes become overactive while others are turned down. These genetic changes can help tumors grow out of control and become more aggressive, adapt to changing conditions, and eventually lead the tumor to metastasize and spread elsewhere in the body.

From Massachusetts Institute of Technology (MIT) 24 Jul 2020

Researchers identify the role of calcium channel subunits in synapse development

The ability of the human brain to process and store information is determined to a large extent by the connectivity between nerve cells. Chemical synapses are very important in this context as they constitute the interface for the transmission of information between individual nerve cells.

23 Jul 2020

Genes News and Research

Study may lead to new therapeutic approaches against coronaviruses

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

Movement of small RNAs underlies mobile RNA interference

Supercomputer analyses point to a new pathway for COVID-19 inflammatory response

Scientists map the genome of aphid-like pest that decimates vineyards

Deep learning algorithm can infer molecular alterations in cancer from histology images

Biologists identify a molecular mechanism that underlies phenotypic plasticity

Human genome may explain the neonatal origins of immune and inflammatory diseases

Study sheds new light on core regulatory networks that govern cell types in vertebrates

New technology helps visualize entire genome at molecular resolution

Study pinpoints the miRNA that promotes hair follicle growth

A novel approach to identify cancer targets using 'synthetic lethality'

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Artificial intelligence-based process can help design novel proteins

Research identifies TLR7 gene that predisposes individuals to severe COVID-19

Computational tool can help study APA mechanism that regulates gene expression

Study shows how cancer develops resistance to chemotherapy

Study shows KBTBD2 gene plays a key role in regulating insulin sensitivity

Epigenomic data can help characterize genes that play key role in cancer progression

Researchers identify the role of calcium channel subunits in synapse development

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