Proliferation News and Research

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New study shows promise for developing COVID-19 vaccine

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

24 Aug 2020

Study shows how PIM kinases enhance the motility of cancer cells

PIM kinases are essentially enzymes that support the metastatic growth and proliferation of tumor cells.

20 Aug 2020

Novel molecular survival strategy of Shigella bacterium uncovered

Enteric pathogens, such as the bacterium Shigella, can cause severe intestinal disease with bloody diarrhea. In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered a novel molecular survival strategy by which Shigella is able to cause damage to the intestines despite two elaborate protective mechanisms used by host cells.

19 Aug 2020

New nanoparticle formulation could stop tooth decay without killing oral bacteria

Oral bacteria are ready to spring into action the moment a dental hygienist finishes scraping plaque off a patient's teeth.

18 Aug 2020

Scientists describe the mechanism of action of therapeutic antibodies

Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells.

14 Aug 2020

Hydrogels based on modified pectins could be used for neural tissue restoration

Far Eastern Federal University (FEFU) scientists have developed implantable hydrogels based on plant polysaccharides (pectins). They can play the role of an artificial extracellular matrix, a special network of molecules that fills the space between body cells.

14 Aug 2020

Study shows how FAK protein is activated on lipid membranes

A team of researchers has recently described the mechanistic details regarding the activation of the Focal Adhesion Kinase (FAK) on lipid membranes.

12 Aug 2020

Mitochondrial reprogramming may offer new treatment strategies against breast cancer

A study performed has revealed that oxygen-deprived breast cancer cells transmit messages that cause oncogenic modifications in the surrounding healthy cells.

11 Aug 2020

Genes linked to Down syndrome abnormalities may offer protection against solid tumors

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

Epigenetics key to daily production of 10 billion blood cells without mistakes

Just one in 2,000 bone marrow cells are hematopoietic stem cells (HSC), but these are the source of the ten billion blood cells humans make every day.

6 Aug 2020

New study may offer a novel, potential target for treating breast cancer

According to researchers, G-quadruplexes have been demonstrated to play a crucial role in specific types of breast cancer for the first time.

5 Aug 2020

Researchers identify how airway cells work together in regeneration and aging

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases -- creating more of themselves and producing mature airway cells -- to regenerate lung tissue after an injury.

28 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Fusion protein found to effective at treating pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

22 Jul 2020

Blood vessels communicate with peripheral neurons to regulate neuronal differentiation

Researchers at Pompeu Fabra University have shown for the first time that blood vessels communicate with neurons in the peripheral nervous system, regulating their proliferation and differentiation.

17 Jul 2020

Researchers evaluate role of zinc in COVID-19 prevention

Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine.

14 Jul 2020

Metagenomic data on intestinal microflora can open up treatments for intestinal dysbiosis

Scientists from Osaka City University, The Institute for Medical Science, and The University of Tokyo have presented intestinal viral and bacterial metagenome data from the fecal samples collected from 101 healthy Japanese persons.

13 Jul 2020

Scientists report detailed proteomic analysis of human lung adenocarcinoma

A team of Chinese scientists from the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, the State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Shanghai Jiao Tong University, recently reported a comprehensive proteomic analysis based on 103 Chinese patients with lung adenocarcinoma (LUAD), a leading cause of death among all types of cancer worldwide.

10 Jul 2020

Research uncovers how 'reubiquitination' promotes elimination of misfolded membrane proteins

Chinese researchers recently discovered a protein quality control mechanism called "reubiquitination".

9 Jul 2020

Importance of Sustainable Food

AZoLifeSciences speaks to Iñigo Charola about the importance of sustainable food production, and how the development of cultured meat can help.

From Biotech Foods 3 Jul 2020