Cholera is an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae. The infection is often mild or without symptoms, but sometimes it can be severe. Approximately one in 20 infected persons has severe disease characterized by profuse watery diarrhea, vomiting, and leg cramps. In these persons, rapid loss of body fluids leads to dehydration and shock. Without treatment, death can occur within hours.
Among those in greatest peril after the devasting earthquakes in the Middle East are some 6.6 million internally displaced persons in Syria, as well as 1.9 million Syrian refugees living in Turkey, according to estimations from the United Nations High Commissioner for Refugees.
Cholera is still an enormous problem. An acute diarrheal disease, there have been seven major pandemics in the last two hundred years. According to the WHO, cholera still kills up to 143,000 people each year and infects up to 4 million others, mostly in poor or underdeveloped countries.
Cholera can kill within hours if left untreated, and it sickens as many as 4 million people a year. In a new article in the journal Cell, researchers describe how gut bacteria helps people resist the disease.
An accumulation of the peptidoglycan recycling pathway that is able to modulate the synthesis and structure of the cell wall has been found by researchers.
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