Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Neural Mechanism Involved in Leptin Resistance Revealed

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

5 Mar 2025

New Approach Could Protect Insulin-Producing Beta Cells from Damage Related to Diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

5 Mar 2025

Study Unveils Phage-Bacteria Dynamics in the Early Life Gut Microbiome

A world of microbes resides within the gut of every human being. This vast microbial community, the microbiome, which includes bacteria and viruses, has repeatedly demonstrated its ability to actively contribute to both health and disease.

26 Feb 2025

Intermittent Fasting Disrupts Development of Insulin-Producing Beta Cells in Young Mice

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice.

17 Feb 2025

Groundbreaking Gene Switch Offers New Hope for Metabolic Disease Treatments

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

17 Feb 2025

PanK4 Protein Could Be Key to Better Control of Blood Sugar and Metabolism

Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr. Maximilian Kleinert at the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE). His team discovered that the protein PanK4 plays a crucial role in the energy metabolism of skeletal muscles.

13 Feb 2025

CRISPR-Engineered Fat Cells Show Promise in Preclinical Cancer Models

Cancer is rarely discussed in the same breath as liposuction or plastic surgery.

5 Feb 2025

Gut Microbes May Explain Link Between Sugar-Sweetened Beverages and Diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

3 Feb 2025

New Insights into Nuclear Lipid Droplets as Regulators of Aging and Metabolic Health

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled "Nuclear lipid droplets: a novel regulator of nuclear homeostasis and aging."

8 Jan 2025

Overactive Chemoreceptors Affect Cardiovascular and Metabolic Consequences of Type 2 Diabetes

Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes.

20 Dec 2024

Researchers Use Bacteria to Convert Plastic Waste Into Human Therapeutics, Including Insulin

A new study from the Manchester Institute of Biotechnology describes a novel biological method to convert mixed municipal waste-like fractions – including food scraps, plastics, and textiles – into valuable bio-products.

9 Dec 2024

Study Offers a New Perspective on the Evolution of Large Human Brains

Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance.

3 Dec 2024

Novel Organoid Model Sheds Light on Human Pancreas Development and Disease

A new organoid that resembles the human fetal pancreas has been created by researchers in the organoid group, providing an understanding of its early development.

3 Dec 2024

Systemic Metabolic Adaptation Supports Tissue Regeneration in Axolotls and Fruit Flies

Regenerating tissues following injury is a demanding task most multicellular organisms master to different levels. In order to better understand the mechanisms common to many species behind tissue regeneration, researchers from the Paul Langerhans Institute Dresden and the BIOTEC (TU Dresden), decided to examine changes in systemic metabolism during regeneration.

29 Nov 2024

Reduced Protein Mobility Linked to Chronic Diseases and Their Complications

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

28 Nov 2024