Manufacturing News and Research

RSS

Manufacturing is the production of products across all industries, on a large-scale, using machinery.

RION Engages Lonza to Scale Manufacturing Exosome Based Therapeutics

RION, a commercial and clinical-stage regenerative medicine company pioneering platelet-derived exosomes for both human and animal health applications, has announced a collaboration with Lonza, one of the world’s largest contract development and manufacturing organizations (CDMOs), to provide cGMP manufacturing and technical support for commercial scale production of its Purified Exosome Product™ (PEP™) drug substance for late phase clinical supply and beyond.

From Lonza 26 Sep 2025

How Cells Work Together to Sense Beyond Their Surroundings

The story of the princess and the pea evokes an image of a highly sensitive royal young woman so refined, she can sense a pea under a stack of mattresses.

15 Sep 2025

Scientists Engineer E. Coli To Produce Plastic-Building Chemical

This study reveals a novel pathway in E. coli for synthesizing 2,5-pyridinedicarboxylate from glucose, offering a sustainable alternative to fossil fuels.

10 Sep 2025

New Research Highlights a More Efficient CAR T Treatment

This review article focuses on the transformative potential of in vivo CAR T cell treatment in overcoming the constraints of standard CAR T cell production.

8 Sep 2025

BioDlink Fast-Tracks Global Growth with Bevacizumab Launch in Colombia and Pakistan

BioDlink announced that its self-developed bevacizumab injection biosimilar has received marketing approval from Colombia’s National Institute for Surveillance of Medicines and Foods (INVIMA) and Pakistan’s Drug Regulatory Authority of Pakistan (DRAP).

8 Sep 2025

BioDlink Expands Ecosystem Alliance to Empower Biotech Innovators Worldwide

As BioDlink, a leading global CDMO, affirms its commitment to strategic alliances to support biotech innovation worldwide as it marks 15 years of operations.

From BioDlink 5 Sep 2025

Mitsui, QSimulate, and Quantinuum Launch “QIDO”: A Quantum-Integrated Chemistry Platform Targeting Faster Drug and Materials Discovery

Mitsui & Co., Ltd. (“Mitsui”), QSimulate, and Quantinuum today announced the launch of a new quantum-integrated chemistry platform, QIDO (Quantum-Integrated Discovery Orchestrator).

From Quantinuum Ltd 22 Aug 2025

Machine Learning Model Accounts for Biological Variability in Culture Media Design

Cell culture is a foundational technology widely used across fields such as pharmaceutical production, regenerative medicine, food science, and materials engineering. A critical component of successful cell culture is the culture medium-a solution containing essential nutrients that support cell growth.

21 Aug 2025

Automated 15-minute, Aseptic Micro-Sampling of T Cells

Auto-CeSS is an automated system for aseptic 30 μL sample collection, enhancing process monitoring and reducing contamination in cell therapy manufacturing.

13 Aug 2025

Elegen and Nutcracker Therapeutics to Pilot First Fully Cell-Free Manufacturing Process for RNA-based Personalized Cancer Therapeutics

Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, today announced the launch of a pilot program to demonstrate the industry's first fully synthetic, cell-free manufacturing platform for RNA-based personalized cancer therapeutics (PCTs).

From Elegen 15 Jul 2025

UAB Identifies Six Novel Subsets, Reshaping Immune Knowledge

The study highlights T-bet's importance in memory B cells, essential for rapid antibody production and sustained immune defense against influenza.

14 Jul 2025

Iowa State Engineers Reinvent Gene Gun for Faster and Safer Crop Editing

Plant scientists have used a standard "gene gun" since 1988 to genetically modify crops for better yield, nutrition, pest resistance and other valuable traits.

5 Jul 2025

New Stem Cell Reports Perspective: Biomanufacturing in Low Earth Orbit

A new perspective article just published in Stem Cell Reports, “Biomanufacturing in low Earth orbit: A paradigm shift,” features insights from the ISS National Laboratory’s very own Program Director for In-Space Biomanufacturing Davide Marotta, Deputy Chief Scientist Donna Roberts, and Chief Scientist Michael Roberts, as well as leading researchers in regenerative medicine.

3 Jul 2025

Genetically Modified Yeast Turns Urine into Bone Material

Genetically modified yeast transforms human urine into hydroxyapatite, a valuable biomaterial for bone repair, enhancing wastewater treatment efficiency.

18 Jun 2025

New Platform Technology Promises to Generate Hard-to-Get Human Cells

This study presents a fast method for generating human microglia from iPSCs, paving the way for breakthroughs in neurodegenerative disease research.

11 Jun 2025

Waters Acquires Halo Labs, Expanding Biological Analysis Portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

23 May 2025

Wuxi Biologics Completes First Commercial PPQ Campaign at 15,000L Production Line in Hangzhou Site

WuXi Biologics ("WuXi Bio"), a leading global Contract Research, Development and Manufacturing Organization (CRDMO), announced the successful completion of the first commercial project Process Performance Qualification (PPQ) campaign for its three sets of 5,000L single-use bioreactors (SUBs) in the second drug substance line of its MFG20 facility at the Hangzhou site.

16 May 2025