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Tumor Cell Adhesion Could Help Predict Breast Cancer Spread

By assessing how "sticky" tumor cells are, researchers at the University of California San Diego have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread.

6 Mar 2025

Innovative Screening Method Targets Specific Tissues for Drug Delivery

A method developed by a research group at Tampere University seeks specific molecules that can target desired tissues through the bloodstream and penetrate tissues by passing through cells.

27 Feb 2025

Unlocking Cancer’s Secret Strategy: Tumor Cells Work Together To Survive

Research uncovers tumor cell cooperation via CNDP2, suggesting new therapeutic strategies that disrupt nutrient sharing to inhibit cancer growth effectively.

25 Feb 2025

Using CRISPR-Cas9 Gene Editing for Chromosomal Rescue in Down Syndrome

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study.

19 Feb 2025

CN Bio Introduces PhysioMimix DILI Assay Kit to Enhance Drug Safety Testing

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix® DILI assay kit: Human 24.

10 Feb 2025

New CRISPR Tool Reveals Key Lymphoma Genes

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

7 Feb 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

Unveiling the Architecture of Native NMDA Receptors in the Mammalian Brain

A research team led by Shujia Zhu from the Chinese Academy of Sciences’ (CAS) Center for Excellence in Brain Science and Intelligence Technology and Yang Li from the Shanghai Institute of Materia Medica of CAS examined the architecture and assembly of endogenous N-methyl-ᴅ-aspartate receptors (eNMDARs) in the cerebral cortex and hippocampus of adult mammals in a study published in Cell on January 23rd, 2025.

27 Jan 2025

AI-designed proteins revolutionize snakebite treatment

Research highlights the potential of deep learning in creating proteins that neutralize snake venom, offering new solutions for neglected tropical diseases.

24 Jan 2025

RNA, Not DNA, Drives Acute Sunburn and Skin Damage

Sunburn has traditionally been attributed to UV-induced DNA damage. However, a new study by the University of Copenhagen and Nanyang Technological University, Singapore, reveals that RNA, another vital cellular molecule, plays a major role in triggering acute sunburn reactions.

20 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Base Editing Technique Extends Lifespan in Prion Disease Mouse Model

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Novel Targets for Modulating the Gut Microbiota and Human Health

Researchers at the Helmholtz Institute for RNA-based Infection Research and the Julius-Maximilians-Universität in Würzburg have discovered a protein and a class of small ribonucleic acids (sRNAs) in Bacteroides thetaiotaomicron that control the metabolism of sugar.

10 Jan 2025

New Insights into How Nitrogenase Enzyme Survives Oxygen Exposure

Nitrogen is an essential component in the production of amino acids and nucleic acids - both necessary for cell growth and function.

9 Jan 2025

New Gene Editing Tool Targets Alzheimer's by Skipping Disease-Causing Gene Segments

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

24 Dec 2024

Hierarchical Nanostructures Enhance Ultrasound and Drug Delivery

Hierarchical nanostructures facilitate acoustic trapping in dynamic systems, offering new avenues for drug delivery and real-time imaging in biomedical fields.

23 Dec 2024

New Method for Discovering Antibiotics from Bacteria

Numerous natural products produced by microorganisms can be utilized as active ingredients to treat illnesses like cancer and infections.

16 Dec 2024

Study Reveals Mechanism Behind T Cells' Cancer-Killing Power in Hypoxia

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective.

16 Dec 2024

New Genetic Insights into Craniofacial Defects and Embryonic Development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

16 Dec 2024

AI Creates the First Virtual Human Cell

A team of scientists from Stanford University, Genentech, and the Chan-Zuckerberg Initiative claims that science has an “unprecedented opportunity” to use artificial intelligence (AI) to create the first virtual human cell in history, pointing out that recent advancements in AI and the availability of extensive experimental data about human biology have reached a critical mass.

13 Dec 2024