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Extrachromosomal DNA Discovered as a Hidden Factor in Pancreatic Cancer Survival

Pancreatic cancer is one of the deadliest cancers worldwide, with a five-year survival rate of 13%.

14 Mar 2025

Bispecific antibodies for SARS-CoV-2 variant neutralization

Bispecific antibodies targeting multiple SARS-CoV-2 sites offer enhanced neutralization against emerging variants, advancing COVID-19 treatment strategies.

14 Mar 2025

Landscape Transcriptomics Sheds Light on Bee Stress and Decline

A new method of examining gene expression patterns called landscape transcriptomics may help pinpoint what causes bumble bees stress and could eventually give insight into why bee populations are declining overall, according to a study led by researchers at Penn State.

14 Mar 2025

Fruit Fly Study Reveals Temperature's Role in Brain Development and Behavior

The rate of development of poikilothermic animals, such as insects, fish, and reptiles, is determined by environmental temperature.

14 Mar 2025

UCL Study Reveals How Our Brains Simplify Social Interactions

Our brains use basic 'building blocks' of information to keep track of how people interact, enabling us to navigate complex social interactions, finds a new study led by University College London (UCL) researchers.

14 Mar 2025

Researchers Develop New Method for Assembling DNA Nanostructures

University at Albany researchers at the RNA Institute are pioneering new methods for designing and assembling DNA nanostructures, enhancing their potential for real-world applications in medicine, materials science and data storage.

13 Mar 2025

Study Reveals How DNA Reorganization Helps Cells Survive UV Damage

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer.

13 Mar 2025

Generative AI Enhances Spatial Gene Expression Analysis in Tissue Samples

Spatial transcriptomics is an advanced technique that analyzes gene expression within tissue sections, such as those from the heart, skin, or liver. These analyses offer valuable insights into how spatial organization influences cellular functions across various biological contexts and diseases.

13 Mar 2025

Modeling Genetic Disruptions in Heart Development

In the process of heart development, cells move around and interact with one another to establish their positions, with significant implications: pairing with an incorrect cell can determine whether the heart functions properly or not.

13 Mar 2025

Molecular Intelligence Simplifies Cryo-EM Data Analysis with AI

Scientists from Purdue University’s College of Science and the Rosen Center for Advanced Computing have established Molecular Intelligence, a software company dedicated to assisting researchers in determining the 3D structures of biomolecules captured through cryogenic-electron microscopy (cryo-EM).

13 Mar 2025

New Cannabinoid Drug Brings Hope For Treating Chronic Pain Without Addiction

VIP36, a new CB1 agonist, targets a cryptic pocket to provide analgesia for chronic pain while minimizing side effects and avoiding opioid-related risks.

13 Mar 2025

Researchers Create 'Colocatome' to Study Tumor Cell Interactions

Even cells experience peer pressure. Scientists have long studied the ins and outs of cancer cells to learn more about the disease, but they're increasingly finding that noncancerous cells near the cancer cells exert a powerful influence over a tumor's trajectory.

13 Mar 2025

Study Finds Key Mechanism Behind Plasma Cell Migration for Lasting Immunity

Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections.

13 Mar 2025

Novel Tool Uses DNA Barcode System for Deep-Tissue RNA and Protein Imaging

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the genome controls development and needed to image hundreds of RNA molecules in a thick tissue sample to understand where and how genes were being expressed in cells.

13 Mar 2025

Study Explores the Physiological Role of Nwd1 Gene in MASH Pathogenesis

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

12 Mar 2025

Can We Engineer Crops to Withstand Climate Change and Increasing Temperatures?

Investigating heat stress in crops, this review highlights genetic adaptations and CRISPR techniques to develop resilient varieties for sustainable agriculture.

12 Mar 2025

Scientists Develop Off-the-Shelf Vascular Grafts Using Stem Cells

Zhang, J., et al. (2025) Small-diameter artery grafts engineered from pluripotent stem cells maintain 100% patency in an allogeneic rhesus macaque model. Cell Reports Medicine. doi.org/10.1016/j.xcrm.2025.102002.

12 Mar 2025

Study Reveals How Tuberculosis Bacteria Survive Airborne Journey

Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person's lungs to another person's during coughing, sneezing or talking, according to researchers from Weill Cornell Medicine and the Massachusetts Institute of Technology.

12 Mar 2025

Combination of Viral Antibodies and Genetic Risk Factors Linked to Increased MS Risk

In multiple sclerosis (MS), antibodies to the common Epstein-Barr virus can accidentally attack a protein in the brain and spinal cord. New research shows that the combination of certain viral antibodies and genetic risk factors can be linked to a greatly increased risk of MS.

12 Mar 2025