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Genetically Engineered Mice May Accelerate Anti-Aging Research

Washington State University scientists have created genetically-engineered mice that could help accelerate anti-aging research.

5 Feb 2025

Study Uncovers Mechanisms for RNA Transport and Heritable Gene Regulation

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies.

5 Feb 2025

New Genomic Toolkit Offers Hope Against Superbugs

Amid growing concerns about antibiotic-resistant infections, an international team of microbial experts has introduced a robust and versatile free online genomic toolkit designed to accelerate the development of phage therapy.

5 Feb 2025

Revolutionary Model Identifies Tumor-Fighting Immune Cells in Lung Cancer

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

4 Feb 2025

Scientists Decode ApoB100 Structure for Targeted Heart Disease Treatments

Low-density lipoproteins (LDL) - commonly known as bad cholesterol - have long been on scientists' radar as a major contributor to heart disease.

4 Feb 2025

Gut Microbes May Explain Link Between Sugar-Sweetened Beverages and Diabetes

It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear.

3 Feb 2025

Scientists Design Ultra-Stable Synthetic Proteins That Could Change Drug Discovery

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology, transforming protein engineering.

3 Feb 2025

New Method Helps Detect Mutations Causing Immune Escape in Viruses

Viruses are masters at disguise. When they are pushed too far by our immune system, they send new virus variants into play that are no longer recognized by immune cells.

31 Jan 2025

Studies Reveal Early Resistance to Newly Developed Antibiotics

Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics. Two recent studies, published just days apart in Nature Microbiology and Science Translational Medicine found that resistance can develop against new antibiotics even before they are widely used, compromising their effectiveness from the start.

31 Jan 2025

Novel Chemo-Optogenetic Systems Offer Spatiotemporal Precision

A research team at Umeå University has created advanced light-controlled tools that allow for precise regulation of proteins in real time within living cells.

31 Jan 2025

Researchers Apply Advanced AI Genetics Models to Study Parkinson's Disease

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved drugs that can potentially be repurposed for PD treatment.

29 Jan 2025

Scientists Create First Healthy Mice with Two Fathers

A group of stem cell researchers has successfully engineered embryonic stem cells to create a bi-paternal mouse, a mouse with two male parents, that survived to adulthood.

29 Jan 2025

New Lipids Dramatically Improve Gene Therapy and Vaccine Delivery

Every time a shuttle docks with the International Space Station (ISS), a precise and intricate process takes place between the shuttle’s docking system and its counterpart on the station

29 Jan 2025

New Protein Structures Could Lead to Better Treatments for Transthyretin Amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

New Method Helps T Cells Live Longer and Fight Cancer More Effectively

Researchers from the University of Pittsburgh have developed a new way to grow T cells in the lab that enables them to live longer and better destroy cancer cells in a mouse model of melanoma compared to those grown in traditional growth media.

29 Jan 2025

Unique Genetic Signature Predicts Bacteria's Potential to Develop Antibiotic Resistance

Antibiotic resistance is a global public health crisis responsible for more than a million deaths annually.

29 Jan 2025

New Epigenetic Tool Can Track Androgen Exposure Over Time

Researchers from the University of Otago – Ōtākou Whakaihu Waka have created a world-first epigenetic tool which has implications for medicine, sports, and agriculture.

28 Jan 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

Digoxin Weakens Cancer’s Spread by Targeting Cell Clusters

Some tumor types spread throughout the body and develop metastases instead of staying at their original location.

27 Jan 2025

Scientists Uncover an Immune System Power Play Behind Bee Venom Allergy

Monash University scientists have identified an immune system power play behind serious bee venom allergy, which lands twice as many Australians in hospital emergency departments each year as snake or spider bites.

25 Jan 2025