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spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

8 Sep 2025

New Research Highlights a More Efficient CAR T Treatment

This review article focuses on the transformative potential of in vivo CAR T cell treatment in overcoming the constraints of standard CAR T cell production.

8 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Discovery of De Novo Genes Sheds Light on Peach Evolution and Traits

The emergence of new genes is a central driver of evolutionary innovation. While mechanisms such as duplication and horizontal gene transfer have been widely studied, de novo gene birth represents a unique pathway where functional genes arise from noncoding DNA.

8 Sep 2025

New Computational Tool Tracks How Genetic Variants Affect mRNA Stability

A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas - if their cars don't break down on the way.

8 Sep 2025

Ancient Plant Protein Unlocks New Strategy for Engineering Disease-Resistant Crops

Researchers led by Ken Shirasu at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have identified an ancient protein that has the potential to help defend plants against tens of thousands of different bacteria and other pathogens.

5 Sep 2025

Stress Reshapes Brain Cells and Alters Activity in Mice

Canadian researchers show that stress modifies the morphology of brain cells in mice, directly influencing the rodents' level of physical activity.

5 Sep 2025

Earth BioGenome Project Aims to Build a Digital Library of All Life

From the mighty blue whale to the humble baker’s yeast, scientists have barely begun to understand the vast genetic diversity among lifeforms.

5 Sep 2025

Targeting the Oral Metagenome to Boost Healthy Bacteria

Professor Zhang, a chemical and biomolecular engineering professor at UC Berkeley, is working to distinguish between the healthy and unhealthy bacteria in the human mouth. Her goal is to promote a probiotic oral microbiome by increasing the population of beneficial bacteria.

5 Sep 2025

CRISPRi Screening Reveals Genetic Insights into Cyanobacteria Acclimation

Cyanobacteria are the most abundant photosynthetic microorganisms on Earth. They live in nearly every habitat throughout the world, from permafrost to hot springs and from soils to oceans.

5 Sep 2025

Scientists Identify Human Proteins Essential for SARS-CoV-2 Infection and Replication

Despite vaccines and treatments, SARS-CoV-2-the virus that causes COVID-19-continues to pose a global health threat, driven by new variants and its ability to hijack human cells in ways that still aren't fully understood.

5 Sep 2025

Intestinal Cells Pull Rather Than Push to Remove Weaker Neighbors

Cells on the inner surface of the intestine are replaced every few days. But, how does this work? It was always assumed that cells leave the intestinal surface because excess cells are pushed out. In a recent publication in the journal Science, researchers of the Hubrecht Institute and AMOLF show that this is not correct.

4 Sep 2025

Mechanical Forces Influence the Evolution of Innovations in Early Development

A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.

4 Sep 2025

Scientists Uncover Hidden Role of Cas9 in Building Bacterial Immune Memory

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could use to edit the DNA of living cells.

4 Sep 2025

Microbial Signatures Help Distinguish Colorectal Tumors from Other Cancers

Colorectal cancer is unique in having its own microbial 'fingerprint' – according to new research from the University of East Anglia.

4 Sep 2025

First Complete Map of Plant Stress Response System Unveiled

Researchers have created the world's first complete map of a crucial cellular system that helps plants respond to stress.

4 Sep 2025

Novel Fluorescent Reporter Technology Enables Real-Time Visualization of Apoptosis Inside Cells

Cells in our body are programmed to die after a certain period of time-a natural process known as apoptosis or "cell suicide."

4 Sep 2025

AI Tool for Designing Antibiotics from Scratch

In a recent Cell Biomaterials study, University of Pennsylvania researchers offer AMP-Diffusion, a generative AI tool for creating tens of thousands of novel antimicrobial peptides (AMPs) — short strings of amino acids that serve as the building blocks of proteins — with bacteria-killing capability.

3 Sep 2025

Ancient Microbial DNA Recovered from Million Year Old Mammoth Remains

An international team led by researchers at the Centre for Palaeogenetics, has uncovered microbial DNA preserved in woolly and steppe mammoth remains dating back more than one million years.

3 Sep 2025

Unlocking the Secrets of Lignin Digestion in Soil Microbes

For years, scientists have marveled at bacteria's ability to digest the seemingly indigestible, including carbon from lignin, the tough, woody material that gives plants their rigidity.

3 Sep 2025