Molecule News and Research

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Triglyceride Cycling Process Modifies Stored Fatty Acids

Fat molecules serve as energy storage for fat cells. They consist of three fatty acids attached to a backbone of glycerol.

4 Apr 2023

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.

4 Apr 2023

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

Researchers Uncover a New, Direction-Dependent Friction in Proteins

An interdisciplinary research team of the Institutes of Physical Chemistry and Physics of the University of Freiburg and the Max Planck Institute of Biophysics in Frankfurt-am-Main has discovered a new, direction-dependent friction in proteins called anisotropic friction.

3 Apr 2023

"Visual Biochemistry" Approach to Understand How the BRCA2 Protein Binds and Interacts with DNA

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

3 Apr 2023

First Steps Driving Antibiotic Resistance Discovered

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

3 Apr 2023

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Shigella bacteria can infect humans but not mice. In the March 29 issue of Nature, a team from UConn Health explains why. Their findings may explain the multifariousness of a key weapon of our immune system.

31 Mar 2023

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

31 Mar 2023

First atomic-level structure of 'oil-eating' enzyme paves way for bioengineered catalysts

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively cuts carbon-hydrogen bonds-;the first and most challenging step in turning simple hydrocarbons into more useful chemicals.

31 Mar 2023

Study helps understand at the cellular level how physical activity contributes to fitness during aging

Regular exercise can guarantee quality of life and longevity, specialists agree. However, exactly how exercise influences the functioning of muscle cells is poorly understood.

30 Mar 2023

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

A National Eye Institute-led team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

30 Mar 2023

Study reports a new target to fight against antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

30 Mar 2023

Artificial cells to serve as the powerhouse of the future

Chloroplasts and mitochondria are responsible for producing energy in nature, which is essential for creating sustainable, artificial cells in the lab. In addition to being “the powerhouses of the cell,” as the adage from middle school biology goes, mitochondria are also one of the most difficult intracellular components to artificially clone.

30 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

New inhibitor molecule disrupts the infection mechanism of SARS-CoV-2 coronavirus

A team of scientists led by the Department of Energy's Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

29 Mar 2023

Molecule News and Research

Triglyceride Cycling Process Modifies Stored Fatty Acids

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

Researchers Uncover a New, Direction-Dependent Friction in Proteins

"Visual Biochemistry" Approach to Understand How the BRCA2 Protein Binds and Interacts with DNA

First Steps Driving Antibiotic Resistance Discovered

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

First atomic-level structure of 'oil-eating' enzyme paves way for bioengineered catalysts

Study helps understand at the cellular level how physical activity contributes to fitness during aging

FDA-approved compound promotes photoreceptor survival in lab models of inherited retinal ciliopathy

Study reports a new target to fight against antibiotic-resistant pneumonia

Artificial cells to serve as the powerhouse of the future

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

New inhibitor molecule disrupts the infection mechanism of SARS-CoV-2 coronavirus

Determining the structure of protein pumps using cryo-EM

Beneficial microbes in the infant gut use nitrogen from human milk to support pediatric development

New compound may offer a way to prevent serious C. diff infections

Key gene involved in crop alkaline tolerance discovered

New breakthrough in controlling plant responses to temperature

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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