Tumor News and Research

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Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Scientists from the University of Notre Dame have found a new way for tumor cells to transmit genetic material to other cells in their microenvironment, allowing cancer to spread.

1 Apr 2022

Study on key protein offers clues into the origin of mesothelioma

Researchers at the University of Colorado Anschutz Medical Campus and their international collaborators have discovered that a protein critical in the embryonic stages of life is reactivated in certain cases of mesothelioma, offering clues into the origin of this aggressive cancer.

30 Mar 2022

New approach to assess motility and invasive capacity of cancer cells in a tissue section

There are many proteins involved in the spread of cancer. However, some of them are notably difficult to observe in patient tissue samples.

28 Mar 2022

Multiple nanobodies effectively block infection with different SARS-CoV-2 variants

Researchers at Karolinska Institutet in Sweden have developed a novel strategy for identifying potent miniature antibodies, so-called nanobodies, against emerging SARS-CoV-2 variants.

28 Mar 2022

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet.

25 Mar 2022

New discovery likely to result in cancer vaccine development

According to research published in eLife, researchers have developed a pipeline for detecting, prioritizing, and testing potential tumor antigens for the rapid development of cancer vaccines.

23 Mar 2022

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

Scientists develop a new approach that efficiently integrates information from parallel gene-expression profiling methods at single-cell resolution.

23 Mar 2022

Researchers investigate genomic data discrepancies among racial groups

The Cancer Genome Atlas, one of the biggest cancer research databases, was used by Mayo Clinic researchers to investigate disparities in genomic data quality.

21 Mar 2022

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Natural killer (NK) cells, which are part of the body’s innate, or first-line, immune response, interact with tumor cells, viral infections, and solid organ transplants, according to a new study.

21 Mar 2022

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Researchers have created a novel method that allows them to correlate particular genes to complex tumor properties at a size and resolution that has never been achievable.

21 Mar 2022

Yale researchers find a way to 'supercharge' tumor-attacking T cells

Yale scientists have identified a way to "supercharge" tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat.

11 Mar 2022

Study shows that mechanical stress help cancer cells metastasize

A recent study shows that compressing cancer cells through tight spaces makes them more violent and helps them avoid cell death.

9 Mar 2022

Unusual partners aid new blood vessel development

Insufficient oxygen to an area like the heart or legs, called hypoxia, is a cue to our bodies to make more blood vessels, and scientists have found some unusual partners are key to making that happen.

9 Mar 2022

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

Researchers at the University of Michigan Rogel Cancer Center found that a cytokine, a category of protein that acts as messengers in the body, and a fatty acid can work together to trigger a type of cell death previously defined by studies with synthetic molecules.

7 Mar 2022

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Scientists at the Centro Nacional de Investigaciones Cardiovasculares have identified a nuclear import mechanism essential for organ growth and development. Manipulation of this mechanism has potential applications in the control of organ growth and organ regeneration.

4 Mar 2022

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells.

3 Mar 2022

Tumor News and Research

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Study on key protein offers clues into the origin of mesothelioma

New approach to assess motility and invasive capacity of cancer cells in a tissue section

Multiple nanobodies effectively block infection with different SARS-CoV-2 variants

CDH17CAR T cells can eliminate solid tumors without damaging healthy tissues

New discovery likely to result in cancer vaccine development

Scientists develop a novel approach, enabling spatial mapping of single-cell data within tissue

Researchers investigate genomic data discrepancies among racial groups

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

Yale researchers find a way to 'supercharge' tumor-attacking T cells

Study shows that mechanical stress help cancer cells metastasize

Unusual partners aid new blood vessel development

Study shows how the release of T-cell cytokine combined with fatty acid leads to ferroptosis

CNIC study uncovers a nuclear import mechanism essential for organ growth and development

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

UH researcher secures $2 million to develop drugs for formerly undruggable cancer targets

Study uncovers genomic drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphoma

Looking at protein activity gives a complete picture of leukemia's weaknesses

Macrophages restore normal functions when transported back to the body, says research

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