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Understanding Cell States Could Lead to More Personalized Leukemia Therapies

Myeloid leukaemias are among the most aggressive blood cancers and have low survival rates. Today, leukaemia patients undergo genetic analysis to identify mutations and select the most appropriate treatment.

26 Feb 2025

New ctDNA Model Enhances Metastatic Cancer Surveillance

In metastatic cancer surveillance, monitoring the actual concentrations of circulating tumor DNA (ctDNA) may be critical. Researchers showed that absolute ctDNA concentration thresholds can be defined to rule out or predict impending cancer progression.

25 Feb 2025

T Cells May Hold the Secret to Fighting Dengue Virus

Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study led by scientists at La Jolla Institute for Immunology (LJI).

25 Feb 2025

Unlocking Cancer’s Secret Strategy: Tumor Cells Work Together To Survive

Research uncovers tumor cell cooperation via CNDP2, suggesting new therapeutic strategies that disrupt nutrient sharing to inhibit cancer growth effectively.

25 Feb 2025

LUC7 Proteins Play Key Role in RNA Splicing Control

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

Immunotherapy Breakthrough Targets Jumbled Proteins in Glioma

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

20 Feb 2025

Dysfunctional Memory B Cells Identified as Key Cancer Therapy Target

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – known as the tertiary lymphoid structure – where they become frustratingly dysfunctional when in close contact with tumors.

20 Feb 2025

New Insights into How MicroRNA Affects Bird Flu in Wildlife

Previously, researchers thought that microRNA was a kind of useless residue in cells and blood. But these tiny threads are far more important than some imagined. Also for those who study wildlife.

19 Feb 2025

Blocking Cholesterol Metabolite May Prevent Parkinson's Disease Progression

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice.

19 Feb 2025

Single-Cell Sequencing Maps Pregnancy's Early Stages

Recent research has produced the first high-resolution molecular image of the equine endometrium, the inner lining of the uterus, before and after embryo implantation.

18 Feb 2025

Intermittent Fasting Disrupts Development of Insulin-Producing Beta Cells in Young Mice

A recent study reveals that age plays a significant role in the outcomes of intermittent fasting. Researchers from Technical University of Munich (TUM), LMU Hospital Munich, and Helmholtz Munich discovered that chronic intermittent fasting disrupted the development of insulin-producing beta cells in young mice.

17 Feb 2025

Groundbreaking Gene Switch Offers New Hope for Metabolic Disease Treatments

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

17 Feb 2025

Lung Cancer Cells Develop Electrical Autonomy to Aid Tumor Growth

Researchers from the Francis Crick Institute have found that some particularly aggressive lung cancer cells can develop their own electric network, like that seen in the body's nervous system.

13 Feb 2025

PanK4 Protein Could Be Key to Better Control of Blood Sugar and Metabolism

Physical activity is not only important for fitness, but also for health. This is confirmed by a new study conducted under the direction of Prof. Dr. Maximilian Kleinert at the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE). His team discovered that the protein PanK4 plays a crucial role in the energy metabolism of skeletal muscles.

13 Feb 2025