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New Synthetic Proteins Boost Efficiency of Genome Editing Tools

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature.

3 Oct 2025

Human Kidney Organoids Offer New Insights into APOL1-Mediated Kidney Disease

Chronic kidney disease (CKD) impacts over 700 million individuals globally and arises from a combination of genetic and environmental influences, along with pre-existing health conditions.

3 Oct 2025

Thermo Fisher Scientific Expands Neurodegeneration Research Capabilities with Launch of Olink® Target 48 Neurodegeneration Panel

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of the Olink® Target 48 Neurodegeneration panel, a high-performance, targeted proteomics immunoassay panel developed to accelerate discoveries in neurodegenerative disease research.

From Olink®- Part of Thermo Fisher Scientific 3 Oct 2025

New SCOPE Tool Transforms Discovery of Gene-Regulating Proteins

A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators.

30 Sep 2025

Scientists Discover Genetic Switch that Controls Candida's Toxin Production

The yeast fungus Candida albicans employs the toxin candidalysin not only to cause infections but also to inconspicuously colonize the oral mucosa—though only in precisely regulated amounts.

29 Sep 2025

Protein Networks Expose New Therapeutic Targets for Alzheimer's

A recent study conducted by the Icahn School of Medicine at Mount Sinai provides one of the most thorough insights to date regarding the interactions of brain cells in Alzheimer’s disease, illustrating protein networks that expose communication breakdowns and highlight potential new therapeutic avenues for treatment.

26 Sep 2025

New Research Challenges the Static View of Chromosome Shape

An international team of researchers from the Francis Crick Institute, Imperial College London, Waseda University, and the Cancer Institute of the Japanese Foundation for Cancer Research has reshaped the concept of chromosome shape, discovering that they are not always stable X-shaped structures but are constantly in flux as cell division occurs.

24 Sep 2025

Chromatin Accessibility Shapes Growth and Stress Response in Blue Mold

Blue mold, caused by Penicillium expansum, is one of the most destructive postharvest diseases, leading to economic losses across fruit supply chains.

23 Sep 2025

Deciphering the Genetic Logic of Terpene Diversity in Plants

Angiosperms, representing nearly 90% of all plant species, dominate terrestrial ecosystems thanks in part to their sophisticated chemical communication systems.

22 Sep 2025

PANoptosis Could Revolutionize Liver Cancer Diagnostics and Treatment

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

22 Sep 2025

Possible Breakthrough in the Development of Effective Biomaterials

Many hopes rested on so-called tissue engineering: With the help of stem cells, skin and other organs could be grown, thereby enabling better wound healing and better transplants.

19 Sep 2025

Unique Cytochrome Protein Holds Key to Plant Survival and Metabolism

Despite their fundamental differences, plants, animals, and fungi share certain metabolic processes.

17 Sep 2025

CRISPR Breakthrough Makes Cacao Plants More Resistant To Deadly Disease

This study shows CRISPR-Cas9 modifications to the TcNPR3 gene in cacao reduce Phytophthora susceptibility, supporting eco-friendly agricultural practices.

17 Sep 2025

Soil DNA Reveals Hundreds of Unknown Bacterial Genomes

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

16 Sep 2025

Study Reveals Stabilizing Effect of Small Molecules on Proteins

For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep proteins (i.e. larger particles) from interacting in undesirable ways.

16 Sep 2025

Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025