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Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response.

17 May 2023

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

17 May 2023

Single-Cell Omics Reveals Cell Types Involved in the Biosynthesis of Plant Natural Products

In a new study published in Nature Chemical Biology, an international team of researchers from the University of Georgia, USA, and the Max Planck Institute for Chemical Ecology in Jena, Germany, presents a promising strategy for elucidating metabolic pathways for plant compounds of medicinal importance.

16 May 2023

Study Finds Methylated CD Derivatives as Effective Stabilizers for Supersaturated Drugs

In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency.

16 May 2023

Brain-Wide Mapping Reveals How Serotonin Affects Animal Behavior

Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs.

16 May 2023

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

16 May 2023

Infections with the Fungus Candida auris on the Rise in Germany

Candida auris is an extremely new species among yeasts from the Candida genus that cause infections in humans: it was only reported in 2009, and no evidence has been found prior to the 1990s.

16 May 2023

Robust AI System Identifies Protein Patterns Within Individual Cells

A highly innovative artificial intelligence (AI) system identified protein patterns within individual cells with world-leading accuracy and speed.

From University of Surrey 16 May 2023

Gut Microbiota Interspecies Interactions may Impact the Efficacy of Antibiotics Against C. Difficile

Clostridioides difficile (C. difficile) is a bacterium that can infect the large intestine, with symptoms ranging from diarrhea to life-threatening colon damage.

12 May 2023

New Method for Analyzing Protein Crystals Could Open Up Applications for Drug Discovery

A new method for analyzing protein crystals – developed by Cornell researchers and given a funky two-part name – could open up applications for new drug discovery and other areas of biotechnology and biochemistry.

12 May 2023

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene.

12 May 2023

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

12 May 2023

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

University of Queensland researchers have used artificial intelligence to build a 3D map of key cell components to better understand dementia and infectious diseases including COVID-19.

12 May 2023

Essential Oil From the Leaves of Labrador Tea Plant Has Antimalarial Properties

Much of what is now considered modern medicine originated as folk remedies or traditional, Indigenous practices. These customs are still alive today, and they could help address a variety of conditions.

12 May 2023

Researchers Use Cheese Rinds to Show Fungal Antibiotics Can Influence Microbiome Development

Fungi produce metabolites that humans have used to improve health. For example, they secrete penicillin, which is then purified and used as an antibiotic for humans, leading to the development of many other antibiotics.

11 May 2023

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Researchers from the University of California, Irvine have developed a DNA enzyme – or DNAzyme – that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact.

9 May 2023

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Researchers created organoids from cancer cells to reduce the need for trial and error in identifying effective cancer treatments in one of many cancer studies scheduled for presentation this week at Digestive Disease Week (DDW) 2023.

9 May 2023

Cancer Stem Cell Test can Accurately Decide More Effective Treatments for Glioblastoma Patients

New multi-institutional phase 3 clinical trial data published May 2 in Cell Reports Medicine found that a cancer stem cell test can accurately decide more effective treatments and lead to increased survival for patients with glioblastoma, a deadly brain tumor.

8 May 2023

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Despite the astounding advances made in understanding the biologic underpinnings of cancer, many cancers are missing obvious genetic drivers.

5 May 2023

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.

5 May 2023

Drugs News and Research

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Single-Cell Omics Reveals Cell Types Involved in the Biosynthesis of Plant Natural Products

Study Finds Methylated CD Derivatives as Effective Stabilizers for Supersaturated Drugs

Brain-Wide Mapping Reveals How Serotonin Affects Animal Behavior

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Infections with the Fungus Candida auris on the Rise in Germany

Robust AI System Identifies Protein Patterns Within Individual Cells

Gut Microbiota Interspecies Interactions may Impact the Efficacy of Antibiotics Against C. Difficile

New Method for Analyzing Protein Crystals Could Open Up Applications for Drug Discovery

Researchers Show a Second Key Gene Involved in Malaria's Resistance to Chloroquine

Prime Editing System Could Accelerate the Study of Cancer-Linked Mutations

AI Used to Create 3D Model of 'Postal Workers' in Human Cells

Essential Oil From the Leaves of Labrador Tea Plant Has Antimalarial Properties

Researchers Use Cheese Rinds to Show Fungal Antibiotics Can Influence Microbiome Development

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Patient-Derived Organoids can Help Identify Effective Personalized Cancer Therapies

Cancer Stem Cell Test can Accurately Decide More Effective Treatments for Glioblastoma Patients

Researchers Create a Computational Tool to Gain New Insights From Multi-Omics Data

Eliminating or Blocking the Tiam1 Gene Prevents, Reverses Chronic Neuropathic Pain

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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