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Research findings likely to enhance genome-based disease prediction

A recent study by the University of Oxford and co-workers identifies that the effects of an individual’s genes on their chance of getting sick declines with age.

31 Aug 2021

Researchers create cardiomyocyte model using a genetic algorithm

Human-induced pluripotent stem cells can differentiate into cardiac myocytes and are employed in applications like formulating patient-specific disease models.

31 Aug 2021

Old habit-controlling neurons may also play a key role in learning new tricks

Imagine working on your computer and typing the same long password you have used for years to access your email.

26 Aug 2021

Novel method improves the resolution of hard X-ray nanotomography

It's been a truth for a long time: if you want to study the movement and behavior of single atoms, electron microscopy can give you what X-rays can't. X-rays are good at penetrating into samples -; they allow you to see what happens inside batteries as they charge and discharge, for example -; but historically they have not been able to spatially image with the same precision electrons can.

25 Aug 2021

Study devises novel process to purify exosomes from cow’s milk

Cells produce exosomes, the nano-sized biological capsules, to protect and courier delicate molecules across the body. The capsules are hard enough to resist enzymatic breakdown and acidic and temperature fluctuations in the bloodstream and gut, which makes them a major candidate for drug delivery.

25 Aug 2021

Stress signal from fat cells could help protect against cardiac damage induced by obesity

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study led by UT Southwestern researchers suggests.

23 Aug 2021

Newly developed premature cells can support early heart development

A research group led by Massachusetts General Hospital has developed premature cells that promote early heart development but disappear soon after birth.

23 Aug 2021

Researchers reveal how ubiquitous signaling molecule plays a critical role in male fertility

Mammalian sperm cannot fertilize an egg from the get-go. It's an ability acquired only after insemination, during passage through the female reproductive tract, and requires two consecutive, time-sensitive processes to provide sperm with the physical and biochemical traits necessary to complete their fundamental job.

From UC San Diego 20 Aug 2021

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

From The University of Utah 20 Aug 2021

Insect olfaction could be used to help develop drug screening techniques

Scientists investigated a key element of the insect olfactory system to analyze how this insight might help humans.

18 Aug 2021

Researchers modify CRISPR to enable antibody-based medical diagnostics

Researchers adapted CRISPR to analyze antibodies in patient blood samples to pave the way for a new class of medical diagnostics.

From Harvard Medical School 16 Aug 2021

Study describes a new method for identifying sperm mutations that can cause disease in children

Throughout development, life and the processes of aging, all human cells accumulate mutations, resulting in what is called mosaicism, a condition in which different cells in the same person have different DNA sequences or genetic makeup.

16 Aug 2021

Research reveals link between high-fat diet, gut microbiota and cardiovascular disease

A high-fat diet disrupts the biology of the gut's inner lining and its microbial communities -; and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

From Vanderbilt University 13 Aug 2021

Understanding computational fluid dynamics can inform more effective design of drug delivery devices

Increased air pollution in recent years has not only contributed to deteriorating environmental conditions in cities across the globe.

12 Aug 2021

Researchers discover DNA signatures linked to cardiovascular diseases

Recent research discovered DNA signatures linked to the risk for cardiovascular disease, a breakthrough that can lead to opportunities for clinical interventions

10 Aug 2021

Muscle protein tied to physical fitness in youth and age-associated diseases

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

9 Aug 2021

Scientists show how lab-grown beating heart cells are vulnerable to SARS-CoV-2 infection

Cambridge scientists have grown beating heart cells in the lab and shown how they are vulnerable to SARS-CoV-2 infection. In a study published in Communications Biology, they used this system to show that an experimental peptide drug called DX600 can prevent the virus entering the heart cells.

6 Aug 2021