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Researchers Identify Natural Compounds for Parasitic Worm Treatment

An international team led by researchers at the University of Toronto has found a family of natural compounds with potential as new and more effective treatments for parasitic worms.

9 May 2024

UCLA Study Reveals Novel Mechanism for Memory Formation During Sleep

UCLA Health researchers have discovered a mechanism that creates memories while reducing metabolic cost, even during sleep.

9 May 2024

Researchers Uncover New Genetic Mutation Linked to Rare Form of Congenital Thyroid Abnormality

A team of researchers from the University of Chicago, in collaboration with the Free University of Brussels and the University of Washington, have uncovered a genetic mutation in a non-coding region of DNA that alters the regulation of the thyroid, leading to a rare form of congenital thyroid abnormality.

9 May 2024

Rice University Develops AI-Powered Tools for Unraveling Microbial Genomes

Since the first microbial genome was sequenced in 1995, scientists have reconstructed the genomic makeup of hundreds of thousands of microorganisms and have even devised methods to take a census of bacterial communities on the skin, in the gut, or in soil, water and elsewhere based on bulk samples, leading to the emergence of a relatively new field of study known as metagenomics.

8 May 2024

mRNA Dynamics Guide Cell Identity Formation

New research from Hebrew University sheds light on the regulation of mRNA during the development of the embryo. The research separates newly-transcribed from pre-existing mRNA in zebrafish embryos using a combination of single-cell RNA-Seq and metabolic labeling.

8 May 2024

New AI Platform Generates Multi-Target Cancer Drug Candidates

Scientists at UC San Diego have developed a machine learning algorithm to simulate the time-consuming chemistry involved in the earliest phases of drug discovery, which could significantly streamline the process and open doors for never-before-seen treatments.

7 May 2024

New Technique Reveals Microscopic Heart Vessels with Unprecedented Clarity

A new imaging technique tested in patients could improve the evaluation of cardiac conditions and undiagnosed chest pain.

7 May 2024

Harnessing Gut Microbiome Compounds to Reduce Inflammation

Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.

6 May 2024

Unlocking Glucose-Driven Mechanisms of Immunosuppression in Glioblastoma

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

6 May 2024

Study Demonstrates How the Warburg Effect is Crucially Linked to Cancer Progression

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming.

3 May 2024

Circadian Coordination: Key to Tissue Function and Aging Prevention

Discovered in the 1970s, circadian clocks are essential for the regulation of biological time in most cells in the human body.

3 May 2024

St. Jude Scientists Reveal Role of Non-Coding DNA Variants in Childhood Leukemia

St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL).

2 May 2024

Investigating Enhancer Function in Pluripotent Stem Cells

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

30 Apr 2024

Mapping Small Molecule-Protein Interactions for Drug Development

For most human proteins, there are no small molecules known to bind them chemically (so called "ligands"). Ligands frequently represent important starting points for drug development but this knowledge gap critically hampers the development of novel medicines.

30 Apr 2024

Genetic Insights: Safflower Genome Assembly Unlocks Key Traits for Crop Improvement

A research team completes a high-quality chromosome-scale assembly of the 'Chuanhonghua 1' safflower genome.

30 Apr 2024

A New Pathway to Universal Donor Blood

The effort to generate universal donor blood has made a significant step ahead. Researchers at DTU and Lund University identified enzymes that, when combined with red blood cells, could eliminate particular sugars found in the A and B antigens of the human ABO blood types. The findings are reported in the scientific journal Nature Microbiology.

30 Apr 2024

Study Reveals Molecular Assembly of One of the Most Common Anti-Phage Systems

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

29 Apr 2024

Research Reveals Surprising Insights Into Yeast Evolution

University of North Carolina at Charlotte Assistant Professor of Bioinformatics Abigail Leavitt LaBella has co-led an ambitious research study -; published this week in the widely influential journal Science -; that reports intriguing findings made through innovative artificial intelligence analysis about yeasts, the small fungi that are key contributors to biotechnology, food production and human health.

29 Apr 2024

Harmless Particles Enhance Immune Response, Study Finds

Our lungs are bombarded by all manner of different particles every single day. Whilst some are perfectly safe for us, others-;known as pathogens-;have the potential to make us ill.

29 Apr 2024

The Evolution of CRISPR Technology in Combatting Antimicrobial Resistance

Assistant Professor Ibrahim Bitar of the Department of Microbiology, Faculty of Medicine, University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will provide an overview of the molecular biology of CRISPR technology and highlight its potential applications in combating antimicrobial resistance in the second new research review.

29 Apr 2024