OCT News and Research

RSS

St. Jude Researchers Uncover Dual Role of ASPL in Stress Granule Assembly and Disassembly

Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP is a protein essential for breaking up stress granules and has been linked to neurodegenerative diseases.

10 Oct 2025

Optimized Culture Conditions Reveal Hidden Antimicrobial Molecules in Dictyostelium

The cellular slime mold Dictyostelium discoideum is a soil microbe that produces diverse natural products with potential antibiotic activity.

10 Oct 2025

Smart Proteins Bring Precision Drug Delivery Closer to Reality

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint the exact areas of the body where they're needed - and nowhere they're not - can reduce the medicine dosage and avoid potentially harmful "off target" effects elsewhere in the body.

10 Oct 2025

New Genetic Insights Offer Hope for Early Detection of Osteosarcoma

Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.

10 Oct 2025

Genomic-First Approach Offers Potential for Earlier Diagnosis of Rare Disorders

A "genomic-first" approach to screening for rare genetic disorders -identifying specific genetic variants and then studying associated traits and symptoms - can identify these conditions earlier and more frequently than standard genetic testing driven by clinical symptoms, a Geisinger study found.

8 Oct 2025

Multiple Genetic Changes Play Key Role in the Development of Complex Disorders

The genetic roots of a disease or disorder do not always grow into clear cut, easily diagnosed clinical features.

8 Oct 2025

Measuring KIF1A Motor Protein Force with DNA Nanosprings

Cells all require the transport of materials to maintain their function. In nerve cells, a tiny motor made of protein called KIF1A is responsible for that.

8 Oct 2025

New Computer-Driven Strategy Reveals How Membrane Proteins Maintain Stability

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring cells stick together.

8 Oct 2025

Antibody 04_A06 Neutralizes Nearly All Tested HIV Variants in Laboratory Studies

A Cologne-led research team has discovered the antibody 04_A06, which neutralizes the human immunodeficiency virus (HIV) in almost all tested variants in vitro and even overcomes typical resistance mechanisms.

7 Oct 2025

Intergenerational Transmission of Exercise Benefits Mediated by Sperm MicroRNAs

n a recent study published in Cell Metabolism, a collaborative research team led by Chen-Yu Zhang, Xi Chen, and Di-Jun Chen from Nanjing University, together with Tao Zhang from Nanjing Medical University, reported groundbreaking findings in their paper entitled "Paternal exercise confers endurance capacity to offspring through sperm microRNAs."

7 Oct 2025

Study Reveals Tissue-Specific DNA Patterns Used by HIV to Evade Detection

Researchers at Western University and the University of Calgary have discovered how HIV hides in different parts of the body by embedding itself into the DNA of cells in a tissue-specific manner, offering new insights into why the virus is so difficult to eliminate and cure – even decades after infection and treatment.

7 Oct 2025

EZH2 Inhibition Restores Order in Cancer Cell Division and Reduces Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading.

6 Oct 2025

Unveiling the Hidden Alliances Between Plant Roots and Microbes

When we talk about microbiota, we usually think of the one inhabiting our gut. But there is another, less known and equally vital: the plant microbiota.

3 Oct 2025

New Synthetic Proteins Boost Efficiency of Genome Editing Tools

Researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life Sciences (MELIS) and the Center for Genomic Regulation (CRG), have designed and experimentally validated new synthetic proteins that can edit the human genome more efficiently than proteins provided by nature.

3 Oct 2025

Electro-bioprinting as a Tool to Study Early Human Embryonic Development

Bioprinted epiblast-like structures mimic early human embryonic development, offering a scalable, ethical platform to study gastrulation and tissue formation.

11 Jun 2025

3D Printing Collagen Scaffolds with Perfusable Systems for Tissue Engineering

Scientists have developed high-resolution 3D-printed collagen scaffolds with internal perfusion systems, enabling complex, vascularized tissue models that support cell viability, growth, and insulin secretion

6 May 2025

New Software Reveals Unprecedented Insights into Embryonic Heart Development

Researchers have created a new software program that offers previously unheard-of capabilities for viewing inside 3D pictures.

13 Jan 2025

Study Reveals T Cells as Key Players in Complete Viral Infection Control

Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that T cells-white blood cells that can destroy harmful pathogens-can completely prevent viral infection, to an extent previously thought only possible due to neutralizing antibodies.

13 Jan 2025

Yeast Proteins Found to Offer Powerful Emulsifying Action

Mention emulsifiers and many people might be unaware what they are used for, but they are present in many daily products, from food to cosmetics.

18 Dec 2024

New Virus Found to Alter Cell Machinery in Eukaryotic Cells

Julie Thomy, lead author of the study and postdoctoral researcher in the Daniel K. Inouye Center for Microbial Oceanography: Research and Education (C-MORE) and Department of Oceanography in the UH Mānoa School of Ocean and Earth Science and Technology (SOEST)

18 Dec 2024