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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Novel Bacterial Immune Weapon that Starves Viral Invaders

The discovery of Cat1 reveals how CARF effectors use complex structures to inhibit viral replication, advancing our understanding of bacterial immune responses.

19 May 2025

Molecular Mechanism Revealed by Stop-Motion Electron Microscopy

Using electron microscopy, researchers illustrate FusB's role in antibiotic resistance, providing a molecular-level understanding of fusidic acid interactions.

19 May 2025

Decoding a 3-Billion-Year-Old Cyanobacterial Nanodevice

Scientists unveil the structure of a light-harvesting nanodevice in ancient cyanobacteria, revealing insights into early oxygen-producing photosynthesis.

19 May 2025

Single Cell Sequencing Uncovers Hidden Drivers of Severe Celiac Disease

Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease.

17 May 2025

Wuxi Biologics Completes First Commercial PPQ Campaign at 15,000L Production Line in Hangzhou Site

WuXi Biologics ("WuXi Bio"), a leading global Contract Research, Development and Manufacturing Organization (CRDMO), announced the successful completion of the first commercial project Process Performance Qualification (PPQ) campaign for its three sets of 5,000L single-use bioreactors (SUBs) in the second drug substance line of its MFG20 facility at the Hangzhou site.

16 May 2025

Protein Balance Offers Key to Overcoming Immunotherapy Resistance

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy that block specific proteins from slowing the immune response.

15 May 2025

Real Time RNA Tracking in Plants Using Fluorescent Biosensors

RNA acts as a messenger inside cells, carrying instructions from DNA that are translated into proteins that are essential for how cells function.

15 May 2025

Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.

15 May 2025

New Mechanism for Selective Host-Microbe Communication in the Gut

The study reveals how APOL9 selectively binds to gut bacteria, enhancing immune responses and maintaining intestinal health through microbial communication.

15 May 2025

Sustainable Recycling: Turning Expired Pet Food into Biodiesel and Livestock Feed with Black Soldier Fly Larvae

A new study explores the use of black soldier fly larvae to convert expired pet food into biodiesel and animal feed. This sustainable biorefinery approach offers a low-emission, efficient solution for organic waste management and circular meat production.

14 May 2025

How RNA-Binding Proteins and Circular RNAs Shape Tumor Biology

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

13 May 2025

Estrogen Related Receptors Identified as Key to Muscle Energy Restoration

A new Salk Institute study suggests estrogen-related receptors could be a key to repairing energy metabolism and muscle fatigue.

13 May 2025

Unraveling How E. histolytica Kills Cells and Evades the Immune System

Understanding how E. histolytica attacks human cells and evades immunity is crucial for developing effective treatments and vaccines against this parasite.

13 May 2025

Depleting TM6SF2 in the Gut Worsens Liver Fat Buildup, Study Finds

A new study finds that gut-specific TM6SF2 depletion exacerbates liver fat accumulation and dysbiosis in mice on high-fat diets, highlighting its importance in gut-liver metabolic regulation.

12 May 2025

Cryo-EM Reveals Protein-Free RNA Structures in Bacterial Cells

Cryogenic electron microscopy showed for the first time that large RNA complexes can assemble without the help of proteins, expanding our understanding of RNA folding and function.

10 May 2025

AI Designs Synthetic DNA to Control Gene Expression in Mammalian Cells

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

10 May 2025

Scientists Use AI to Predict Future Viruses and Design Better Vaccines

Effective vaccines dramatically changed the course of the COVID-19 pandemic, preventing illness, reducing disease severity, and saving millions of lives.

10 May 2025

Flowers Evolve Stench by Repurposing Detox Genes

Some plants lure pollinators not with sweet fragrances, but with the rank stench of decay. In a new study, researchers show how plants pull this off.

10 May 2025

Unlocking the Molecular Secrets of Sweet Taste Perception

Our enjoyment of sweets can be traced to one subset of taste receptor cells – specialized sweet-sensing cells found in our taste buds – that initiate the chain of reactions driving our strong attraction and appetite for sugar.

8 May 2025

Novel Therapeutic Strategy for Healthy Aging and Longevity

An international study led by the Institut de Neurociències at the UAB (INc-UAB) found that raising levels of the Klotho protein in mice extends lifespan and improves both physical and cognitive health as they age.

8 May 2025