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Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

2 Aug 2024

Geographic Origin Plays Key Role in Tuberculosis Infection, Harvard Study Finds

For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a new study comparing how different strains move through mixed populations in cosmopolitan cities.

2 Aug 2024

Revealing the Spatial Dynamics of Sebum Production

Changes in gene expression in sebaceous glands have been spatially mapped for the first time in a collaborative project between Leipzig University's Interdisciplinary Centre for Bioinformatics (IZBI) and the Faculty of Veterinary Medicine.

1 Aug 2024

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years.

1 Aug 2024

ETH Zurich Researchers Accelerate Bacterial Evolution for Enhanced Cellulose Production

Bacteria produce materials that are of interest to humans, such as cellulose, silk and minerals. The advantage of producing bacteria in this way is that it is sustainable, takes place at room temperature and in water.

1 Aug 2024

Breakthrough Study Reveals Role of Tissue-Resident Memory T Cells in Lung Cancer Prognosis

An extensive analytical study performed at the Terasaki Institute and published in Frontiers in Immunology highlights the crucial role of tissue-resident memory T cells and how they influence the immune environment of patients with non-small cell lung cancer and their overall prognosis.

1 Aug 2024

Researchers Uncover Unique Protective Mechanism in Pancreatic Cells

Researchers from the University of Cologne have revealed a mechanism protecting pancreatic β-cells, which are crucial for insulin production from inflammatory cell death. The study investigated the role of receptor-interacting protein kinase 1 (RIPK1) in regulating β-cell survival.

1 Aug 2024

Swabbing Technique Reveals Diversity of Immune Cells in the Upper Airway

Scientists at La Jolla Institute for Immunology (LJI) have published the first-ever, in-depth analysis of immune cell memory in the upper airways of adult volunteers. Among these immune cells, the researcher spotted "tissue resident" memory cells, which stand ready to defend the airway from SARS-CoV-2 and other respiratory diseases.

1 Aug 2024

Cryo-EM Reveals Structural Differences in Fetal and Adult Muscle Receptors

The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ability to walk, while cows can walk mere minutes after birth and run not long after.

1 Aug 2024

Mucus-Based Bioink Shows Promise for 3D-Printed Lung Tissue

Each year, lung illnesses claim the lives of millions of people worldwide. There are few available treatments, and animal models used to research these conditions and potential drugs are insufficient. Researchers have now successfully developed a mucus-based bioink for 3D printing lung tissue.

31 Jul 2024

Uncovering the Molecular Mechanisms Underlying Liver Regeneration

The liver can renew itself quite well. Maintaining organ function and recuperating from surgery or injury depends on this quality. Using clinical samples, researchers from the University of Leipzig Medical Center, the Max Planck Institute for Evolutionary Anthropology, TU Dresden, and ETH Zurich have examined the changes in liver cell types before and following regeneration.

31 Jul 2024

The Role of Chemical Proteomics in Understanding Small Molecule-Protein Interactions

The various chemical proteomics methods with relevant examples.

31 Jul 2024

Biotium Releases New High-Performance Magnetic Bead-Based FFPE DNA and RNA Extraction Kits Well-Suited for Automated Processes

Biotium, a leading supplier and inventor of fluorescent probes and other novel reagents for life science research, proudly announces the availability of high-throughput compatible magnetic-bead based versions of the CELLDATA DNAstorm™ and RNAstorm™ 2.0 FFPE Extraction Kits. Following the successful 2022 acquisition and integration of Cell Data Sciences' RNAstorm™ and DNAstorm™ kits, Biotium has enhanced these kits to streamline extraction of DNA or RNA from formalin-fixed, paraffin-embedded (FFPE) tissue samples.

From Biotium, Inc. 31 Jul 2024

Rapid Parkinson's Model Opens Door to Personalized Treatments

Scientists at Brigham and Women’s Hospital, a key member of the Mass General Brigham healthcare system, have created a model that swiftly transforms stem cells into brain cells exhibiting protein structures associated with Parkinson’s disease (PD).

30 Jul 2024

Injectable Therapy Using 'Dancing Molecules' Promises New Hope for Cartilage Repair

In November 2021, Northwestern University researchers introduced an injectable new therapy, which harnessed fast-moving "dancing molecules," to repair tissues and reverse paralysis after severe spinal cord injuries.

29 Jul 2024

Study Reveals Widespread Gene Misbehavior in Healthy Humans

Scientists have uncovered that ‘gene misbehaviour’ – where genes are active when they were expected to be switched off – is a surprisingly common phenomenon in the healthy human population.

29 Jul 2024

Innovative Model Creates Personalized Parkinson's Disease Brain Cells for Drug Testing

A new model developed by Brigham researchers rapidly converts stem cells to brain cells characteristic of Parkinson’s disease to create personalized stem cell models with opportunities to test treatments

29 Jul 2024

Harvard Researchers Crack the Code on Western Equine Encephalitis Decline

The story of the rise and fall of western equine encephalitis as a lethal disease offers essential lessons about how a pathogen can gain or lose its ability to jump from animals to humans.

29 Jul 2024

Unraveling the Complexities of X Chromosome Inheritance

A new study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences has reveals that the contribution of cells expressing maternal or paternal X chromosomes can be selectively skewed in different parts of the body.

26 Jul 2024

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

The niche areas in which phenotypic screening continues to be advantageous over the targeted approach, and the recent advances in phenotypic screening technology that have increased their efficiency.

26 Jul 2024

Cell News and Research

Breakthrough Method Captures Aging Impact on Alzheimer’s Disease in Lab-Grown Neurons

Geographic Origin Plays Key Role in Tuberculosis Infection, Harvard Study Finds

Revealing the Spatial Dynamics of Sebum Production

Discovery of Immune Cell Reservoirs Near Glioblastomas Offers New Treatment Possibilities

ETH Zurich Researchers Accelerate Bacterial Evolution for Enhanced Cellulose Production

Breakthrough Study Reveals Role of Tissue-Resident Memory T Cells in Lung Cancer Prognosis

Researchers Uncover Unique Protective Mechanism in Pancreatic Cells

Swabbing Technique Reveals Diversity of Immune Cells in the Upper Airway

Cryo-EM Reveals Structural Differences in Fetal and Adult Muscle Receptors

Mucus-Based Bioink Shows Promise for 3D-Printed Lung Tissue

Uncovering the Molecular Mechanisms Underlying Liver Regeneration

The Role of Chemical Proteomics in Understanding Small Molecule-Protein Interactions

Biotium Releases New High-Performance Magnetic Bead-Based FFPE DNA and RNA Extraction Kits Well-Suited for Automated Processes

Rapid Parkinson's Model Opens Door to Personalized Treatments

Injectable Therapy Using 'Dancing Molecules' Promises New Hope for Cartilage Repair

Study Reveals Widespread Gene Misbehavior in Healthy Humans

Innovative Model Creates Personalized Parkinson's Disease Brain Cells for Drug Testing

Harvard Researchers Crack the Code on Western Equine Encephalitis Decline

Unraveling the Complexities of X Chromosome Inheritance

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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