Genes News and Research

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Open-Access Atlas Maps Roundworm Aging at Single-Cell Resolution

A new aging atlas provides scientists with a detailed view of how individual cells and tissues in worms age, and how various lifespan-extending strategies might halt the aging process.

18 Jun 2024

Breakthrough: Plants Used to Produce Health-Boosting Human Milk Oligosaccharides

A plant-based HMO production platform that utilizes the carbohydrate anabolic ability of plants.

18 Jun 2024

Ancestry Bias can Cause CRISPR Screens to Miss Cancer Dependencies

CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow.

17 Jun 2024

TIMP-1 Protein Enhances Immune Defense Against Cancer

Researchers at the University of Turku in Finland have found a new function for an existing protein.

17 Jun 2024

Gene Editing Yields New Insights into Tardigrade Resilience

Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life.

14 Jun 2024

Study Uncovers Link Between Genetic Variants and Mosaic Loss of X Chromosome in Aging Women

Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman's two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX.

13 Jun 2024

Mitochondria Influence the Ability of Adult Cardiac Cells to Multiply

Whether forcing adult cardiomyocytes to reverse from the oxidative phosphorylation phenotype to the glycolysis phenotype would also restore their mitotic ability.

13 Jun 2024

Simplified Proteomics Method Could Open the Door Toward Precision Medicine

Proteins are workhorses that carry out most of the biological functions in our cells.

12 Jun 2024

AI Uncovers Rare Mutations with Major Impact on Heart Health

Researchers at the Icahn School of Medicine at Mount Sinai have discovered unusual coding variants in 17 genes that provide insight into the molecular causes of coronary artery disease (CAD), the world's leading cause of morbidity and mortality.

12 Jun 2024

Innovative ssREAD Database Provides Rich Alzheimer's Disease RNA-Seq Resources for Researchers

The Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease, or ssREAD.

12 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

CSHL Researchers Reveal New Protein Networks in RNA Splicing Regulation

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes.

11 Jun 2024

Engineered Enzyme Boosts Gene Editing Efficiency for Potential Cystic Fibrosis Treatment

Researchers at the Broad Institute of MIT and Harvard have enhanced a gene-editing technology, enabling it to efficiently insert or substitute entire genes in the genome of human cells.

11 Jun 2024

Innovative Gene Editing Elevates Photosynthetic Efficiency in Food Crops

A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA.

10 Jun 2024

Study Finds Essential Role of Orco Protein in Ant Olfactory Neuron Survival and Social Interaction

While smell plays a considerable role in the social interactions of humans-;for instance, signaling fear or generating closeness-;for ants, it is vitally important.

10 Jun 2024

New research identifies and mitigates bias in CRISPR-Cas9 gene editing

A phenomics approach to study proximity bias and the unrelated chromosomal truncations.

10 Jun 2024

Multiciliated Cell Differentiation Regulated by an Alternative Cell Cycle

A fertilized egg can develop into a baby through the amazing process of cell division, while a malignant cell can become a malignant tumor. Since there is so much on the line, nature maintains strict control over it through a mechanism known as the cell cycle that scientists once believed they thoroughly understood.

7 Jun 2024