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How Immune Cells Decode Cancer's Turbocharged State

When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies.

22 May 2024

The Influence of Inherited Genes on Melanoma Risk

Most people associate skin cancer warnings with sunburn and tanning beds. “Cancer genes” or inherited risks are associated with diseases such as breast and colon cancer.

22 May 2024

Upgraded Nipponbare Genome Assembly Paves the Way for Enhanced Rice Research

A research team has achieved a groundbreaking improvement in the haplotype-resolved genome sequence of the japonica rice cultivar Nipponbare.

21 May 2024

Mapping Neurodevelopmental Disease with High-Throughput In Vivo Perturb-seq

The brain is often referred to as a "black box"-;one that's difficult to peer inside and determine what's happening at any given moment.

21 May 2024

Brookhaven Scientists Unravel Evolutionary Origins of Plant Lignin

Scientists from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected.

20 May 2024

Supercomputer Simulations Unveil Mechanisms of Fruit Fly Wing Development

If fruit fly wings do not develop into the right shape, the flies will die. UC Riverside researchers have learned how fly embryo cells develop as they need to, opening a window into human development and possible treatments for birth defects.

20 May 2024

Phages and Zombie Cells Regulate Abundant Marine Bacteria

The movement of matter and energy required for ocean life is regulated by marine microbes, of these, approximately one-third are members of the bacterial group SAR11.

20 May 2024

Takara Bio Launches PrimeCap T7 RNA Polymerase for mRNA Therapy Development

Takara Bio announces the launch of PrimeCap™ T7 RNA Polymerase (low dsRNA), a mutant T7 RNA polymerase suitable for mRNA therapeutic research and development.

20 May 2024

Study Reveals How tRNA Modification Influences Malaria Drug Resistance

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites’ ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

20 May 2024

Breakthrough in Natural Vanillin Production Using Engineered Enzyme

Vanilla extract is one of the most widely used flavoring compounds in food products and cosmetics.

17 May 2024

Discovery of New Cancer Cell Death Pathway Involving Schlafen11 Gene

Chemotherapy kills cancer cells. But the way these cells die appears to be different than previously understood.

17 May 2024

Sex-Specific Effects of Germline Regulation on Longevity and Repair in Vertebrates

The study revealed unexpected and sex-specific effects of germline regulation on longevity and somatic repair in vertebrates.

17 May 2024

Study: South African Leopards Exhibit Exceptional Genetic Diversity

Researchers say the discovery of very high genetic diversity in leopards found in the Highveld region of South Africa has increased the need for conservation efforts to protect leopards in the country.

16 May 2024

H5N1 Strain Shows Limited Airborne Transmission in Ferrets

The highly virulent H5N1 avian influenza was initially found in dairy cattle in the United States in March, and by May, outbreaks had been reported from nine states. The research was published in the journal Nature Communications.

16 May 2024

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

16 May 2024

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes.

16 May 2024

Discovery of Novel Adrenal Cell Type Linked to Monogamy in Oldfield Mice

What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell, according to a new study published online today in Nature from scientists at Columbia's Zuckerman Institute.

16 May 2024