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Discovery of Ball-and-Chain Mechanism Sheds Light on Ion Channel Regulation

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a "ball-and-chain" channel-plugging mechanism, according to investigators at Weill Cornell Medicine.

5 Mar 2025

New Approach Could Protect Insulin-Producing Beta Cells from Damage Related to Diabetes

Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a harmful condition linked to the progression of type 2 diabetes (T2D).

5 Mar 2025

Arab Pangenome Reference Provides New Path for Advancing Precision Medicine

Creation of a comprehensive genetic representation for more than 2.5 billion people across the Middle East and South Asia could make a major contribution towards advancing precision medicine, a publication in Nature Medicine reveals.

5 Mar 2025

New Insights Into Ageing Revealed

The way in which blood stem cells evolve over a lifespan differs greatly between humans and mice, new research reveals. The findings provide a new understanding of the critical factors that influence tissue ageing.

5 Mar 2025

New Genetic Clues Could Explain Prostate Cancer’s Aggressive Progression

Scientists from UCLA, the University of Toronto and the University of Melbourne have uncovered new genetic clues that explain why some prostate cancers remain slow-growing while others become life-threatening.

4 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Gut Microbes Transform Excreted Glucose into Crucial Fatty Acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

Lactylation Levels Influence Cardiac Development and Regeneration in Mice

This study is led by Dr. Xiaodong Luan (Institute of Clinical Medicine, Peking Union Medical College Hospital), Dr. Shuyang Zhang (Department of Rare Diseases, Peking Union Medical College Hospital) and Dr. He Huang (Shanghai Institute of Materia Medica, Chinese Academy of Sciences).

3 Mar 2025

Researchers Develop Feline Embryonic Stem Cells to Advance Veterinary Medicine

As different as they may seem, humans and cats have similar ailments, but in terms of health care, veterinary regenerative medicine is not as advanced.

28 Feb 2025

New Cancer-on-Chip Tech Could Replace Animal Testing—Faster, Cheaper, More Accurate!

A new modified silicone rubber for cancer-on-chip applications improves cell adhesion and drug testing, paving the way for personalized cancer treatments.

28 Feb 2025

Age-Invariant Genes May Hold the Key to Understanding Aging and Longevity

A new research paper was published in Aging (Aging-US) on January 27, 2025, in Volume 17, Issue 1, titled "Age-invariant genes: multi-tissue identification and characterization of murine reference genes."

27 Feb 2025

Rare Gene Variants Increase Type 2 Diabetes Prevalence in Asian Indian Families

A new study published in Communications Medicine, a Nature publication, details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people.

27 Feb 2025

Innovative Screening Method Targets Specific Tissues for Drug Delivery

A method developed by a research group at Tampere University seeks specific molecules that can target desired tissues through the bloodstream and penetrate tissues by passing through cells.

27 Feb 2025

Advanced Molecular Tools Help Wildlife Researchers Assess Bat Health

How do wildlife researchers know when an endangered population is sick? They can detect infectious microbes in animal waste, but the presence of a microbe doesn't always equate to impactful symptomatic infections.

27 Feb 2025

Study Reveals How Evolving DNA Powers Human Brain Development

A study of artificial human and chimpanzee nerve cells revealed how faster-evolving DNA gives neurons the ability to build increasingly complex brain power.

27 Feb 2025

Study Unveils Phage-Bacteria Dynamics in the Early Life Gut Microbiome

A world of microbes resides within the gut of every human being. This vast microbial community, the microbiome, which includes bacteria and viruses, has repeatedly demonstrated its ability to actively contribute to both health and disease.

26 Feb 2025

Researchers Develop Mycobacteria Strains with Kill Switches for Safer TB Vaccines

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.

26 Feb 2025

New Strategy Targets Bacterial Communication to Combat Pseudomonas aeruginosa

Pseudomonas aeruginosa is notorious for its role in food spoilage and infections, posing a significant threat to both food safety and human health.

26 Feb 2025

New ctDNA Model Enhances Metastatic Cancer Surveillance

In metastatic cancer surveillance, monitoring the actual concentrations of circulating tumor DNA (ctDNA) may be critical. Researchers showed that absolute ctDNA concentration thresholds can be defined to rule out or predict impending cancer progression.

25 Feb 2025

New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025