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Generative AI Decodes the 3D Structure of DNA

Although the genetic sequence is the same in every cell in the body, only a subset of those genes is expressed by each cell.

3 Feb 2025

Coffee's Bitter Taste Linked to Genetics and Roasting Process

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

30 Jan 2025

New Protein Structures Could Lead to Better Treatments for Transthyretin Amyloidosis

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion.

29 Jan 2025

New Epigenetic Tool Can Track Androgen Exposure Over Time

Researchers from the University of Otago – Ōtākou Whakaihu Waka have created a world-first epigenetic tool which has implications for medicine, sports, and agriculture.

28 Jan 2025

Study Unveils Key Genetic Mechanism Behind Antibiotic Resistance in Bacteria

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs.

24 Jan 2025

Synthesizing Inaoside A from Edible Mushroom

Although natural compounds from plants and animals have long been utilized in drug development, the chemical potential of mushrooms is still poorly understood. Inaoside A, a substance obtained from the edible mushroom Laetiporus cremeiporus, has now been effectively synthesized for the first time by Japanese researchers.

24 Jan 2025

New computational strategy enables design of drug-induced protein interactions

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

22 Jan 2025

New Insights into the Structure and Function of a Key Viral Protein

Researchers at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a crucial part of the Nipah virus, a deadly bat-borne infection that has been responsible for human outbreaks every year since its discovery in 1999.

21 Jan 2025

Mapping of Neuronal IL-1R1 Expression in the Mouse Brain Sheds Light on Mood and Memory

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states.

20 Jan 2025

RNA, Not DNA, Drives Acute Sunburn and Skin Damage

Sunburn has traditionally been attributed to UV-induced DNA damage. However, a new study by the University of Copenhagen and Nanyang Technological University, Singapore, reveals that RNA, another vital cellular molecule, plays a major role in triggering acute sunburn reactions.

20 Jan 2025

Researchers Develop Method to Produce Strigolactones Using Microbial Cell Factories

Sometimes just using a different tool makes the job a whole lot easier. A team of researchers co-led by the University of California San Diego has developed a method to produce a special class of plant hormones, known as strigolactones, at unprecedented levels using microbial cell factories.

17 Jan 2025

AI-Powered Platform for Designing Novel Protein Interactions

Researchers at EPFL have opened up a world of possibilities in the computational design of molecular interactions for biomedicine by using deep learning to create new proteins that bind to complexes involving other small molecules, such as hormones or medications.

17 Jan 2025

Compound from Sea Sponge Could be Used as a Chemical Probe for Research

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor effects and also found to have anti-malarial effects.

15 Jan 2025

DNA Stretching: Minimizing Thermal Fluctuations for Imaging

The majority of microscopes can only illuminate objects up to a specific size before the smallest details start to blend together.

15 Jan 2025

Scientists Uncover Key Plant Metabolite to Block Biofilm Development

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

13 Jan 2025

Research Shows How Sleep Clears Brain Waste

A good night's sleep does more than just help you feel rested-it might literally clear your mind. A new study published January 8 in the Cell Press journal Cell shows how deep sleep may wash away waste buildup in the brain during waking hours, an essential process for maintaining brain health.

10 Jan 2025

Scientists Uncover Circuit Controlling Neuron Migration in Brain Development

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

10 Jan 2025

Illuminating RNA Function with Innovative Bioluminescent Probes

The molecule that reads the genetic data contained in DNA is called RNA. Researchers at the University of California, Irvine have found a method to tag RNA with a glowing bioluminescent molecule, which enables them to track RNA in real time as it travels throughout the body.

10 Jan 2025

RNAConnect Debuts The New UltraMarathonRT® RT-qPCR Kit to Improve Reliability Of Gene Expression Analysis

RNAConnect, developer of enzymatic tools for visualizing and manipulating RNA, today announced the release of the UltraMarathonRT® Two-Step RT-qPCR Kit, a next-generation tool for RNA researchers conducting gene expression analysis.

9 Jan 2025

Breakthrough in Nanopore Technology Could Transform Disease Detection

UC Riverside scientists have developed a nanopore-based tool that could help diagnose illnesses much faster and with greater precision than current tests allow, by capturing signals from individual molecules.

3 Jan 2025