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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Rapid Growth of Blood Cancer Driven by a Single Genetic ‘HIT’

A new study has unveiled when chronic myeloid leukaemia, a type of cancer that affects the blood and bone marrow, arises in life and how fast it grows.

10 Apr 2025

DNA Computing Circuits Move Closer to Real-Time Function Inside Living Cells

A comprehensive review titled "From the Test Tube to the Cell: A Homecoming for DNA Computing Circuits?" published Mar. 4 in Intelligent Computing, a Science Partner Journal, highlights progress in operating DNA computing circuits for operation within living cells.

9 Apr 2025

DNA Analysis Sheds Light on Invasive Weed Strategies

A groundbreaking technique for analyzing the DNA of ancient plant specimens has provided researchers with a valuable tool in the fight against the proliferation of invasive plant species.

9 Apr 2025

New Research Further Translates the Language of the Genome

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of human genes.

9 Apr 2025

New Research Reveals Mitochondrial Guardians Linked to Parkinson’s and ALS

Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and amyotrophic lateral sclerosis act as "guardians" of mitochondria, small organelles, or subunits, within a cell that make and store energy and are found in almost all plants and animals.

8 Apr 2025

Spinning Into Resistance: The Flagella’s Hidden Role

A new study from the Hebrew University of Jerusalem reveals that bacterial movement plays a central role in the transfer of antibiotic resistance genes. The research team discovered that the rotation of flagella in Bacillus subtilis acts as a mechanical signal that activates key conjugation genes.

8 Apr 2025

Scientists Capture Dynamic Process of Chromatin Remodeling in Action

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases.

7 Apr 2025

Scientists Discover Epigenetic Marks in Pancreatic Cancer Transition

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

7 Apr 2025

Carbon Dot-Based Fluorosensor Shows Superior Performance in Enterovirus RNA Detection

Scientists from the University of Jyväskylä's Nanoscience Center in Finland have introduced a novel, label-free ratiometric fluorosensor intended for the sensitive and specific detection of enteroviral RNA.

7 Apr 2025

Antibiotic Resistance Through Bacterial Genes Inhibiting Viral Reproduction

Antibiotic resistance is a global health threat that could supplant cancer mortality within a few decades. Researchers at Umeå University, Sweden, found that the emergence of resistance can be explained by how bacteria develop defenses against virus infection.

7 Apr 2025

New Discovery Reveals How Cells Repair Damaged Mitochondrial DNA

Damage to the genetic material of mitochondria – the mitochondrial DNA or mtDNA for short – can lead to diseases such as Parkinson's, Alzheimer's, amyotrophic lateral sclerosis (ALS), cardiovascular diseases and type 2 diabetes.

7 Apr 2025

Scientists Trace Cell Origins to Understand Inner Ear Development

Researchers at Karolinska Institutet have developed a method that shows how the nervous system and sensory organs are formed in an embryo.

4 Apr 2025

DNA Aptamers Offer Precision Attack Against Leukemia Stem Cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

4 Apr 2025

Ancient DNA Reveals Long Isolated North African Lineage

The study provides critical new insights into the African Humid Period, a time between 14,500 and 5,000 years ago when the Sahara desert was a green savanna, rich in water bodies that facilitated human habitation and the spread of pastoralism.

4 Apr 2025

Mapping Larger Tissue Sections Without Specialized Equipment

By creating comprehensive maps of the locations of gene expression in tissue, spatial transcriptomics technologies have made it possible to perform new types of biological assessments.

4 Apr 2025

AI Model Predicts Antibiotic Resistance in Bacteria

An AI model trained on large amounts of genetic data can predict whether bacteria will become antibiotic-resistant.

3 Apr 2025

Unraveling the Flowerpot Snake's Unique Genome

The flowerpot snake, recognized as one of the smallest snakes globally, possesses some remarkable characteristics.

3 Apr 2025

4basebio Receives MHRA GMP Licence for Manufacture and Supply of Synthetic DNA

4basebio PLC (“4basebio”), a company which develops and commercializes the large-scale manufacture of synthetic DNA as well as nanoparticle delivery solutions, today announced that it has received Good Manufacturing Practice (GMP) certification from the UK’s Medicines and Healthcare products Regulatory Agency (MHRA).

3 Apr 2025

Scientists Build Live African Swine Fever Virus From Synthetic DNA Using CRISPR

Utilizing CRISPR-Cas9, scientists reconstitute live African swine fever virus from synthetic genomes, accelerating vaccine development for this deadly virus.

2 Apr 2025

Novel Protein Analysis Technique Offers Fresh Insights into Immune System Disorders

A study conducted by researchers at Oregon Health & Science University has revealed a novel mechanism by which proteins can be modified within cells. This finding may have significant implications for the understanding of immune system functionality.

1 Apr 2025