Receptor News and Research

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Uncovering Key Differences Between Humans and Mice in Cancer Immunotherapy Targets

“Programmed cell death protein 1,” or PD-1, has been considered a key target in cancer therapies since its discovery in the 1990s.

6 Jan 2025

Princeton Engineers Discover How Soil Bacteria Balance Plant Growth and Immunity

To stay healthy, plants balance the energy they put into growing with the amount they use to defend against harmful bacteria.

3 Jan 2025

Unveiling the Impact of Antigen History on CAR-T Cell Function

The memory of previous interactions with bacteria, viruses, and other antigens is carried by some CAR-T cells that have been engineered to fight cancer and other conditions, according to research from the University of Colorado Anschutz Medical Campus.

3 Jan 2025

New Method Improves Quantification of Endocytosis in Living Cells

Living cells and tissues show a high capacity to absorb various chemical compounds from the surrounding environment.

23 Dec 2024

A Novel Method for Synthesizing Piperidines for Modern Medicine

A team of chemists from Scripps Research and Rice University has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study, published in Science, combines biocatalytic carbon-hydrogen oxidation and radical cross-coupling, offering a streamlined and cost-effective approach to create complex, three-dimensional molecules.

19 Dec 2024

Targeting Cancer with Nanoparticle-Delivered Gene Therapy

Scientists are literally shining a laser on the energy centers of cancer cells in an attempt to harm these sources of power and cause widespread cancer cell death.

16 Dec 2024

Programmable G-protein-coupled receptors redefine therapeutic applications.

This study demonstrates the development of PAGERs (programmable antigen-gated engineered receptors), combining antigen specificity, modular adaptability, and drug-controlled activation, with potential applications in synthetic biology, therapeutics, and neuroscience.

12 Dec 2024

Genetic Mutation in the Inherited DNA Found to Drive Breast Cancer Metastasis

Ninety percent of cancer deaths are due to the spread of cancer, not complications from the original tumor.

10 Dec 2024

Single Mutation Could Make H5N1 Bird Flu More Dangerous to Humans

Avian influenza viruses typically require several mutations to adapt and spread among humans, but what happens when just one change can increase the risk of becoming a pandemic virus?

6 Dec 2024

Tool to control cellular activity could advance biology and medicine

A cell’s ability to react to its surroundings is one of its fundamental roles. Therefore, it makes sense that one of the objectives of scientists is to manipulate that process so that cells react to their desires.

5 Dec 2024

Unmasking the Molecular Mechanisms of Hepatitis B Virus Entry

An infection with the hepatitis B virus (HBV), which is spread by blood or bodily fluids, is one of the main causes of chronic liver diseases. The World Health Organization reports that there are 1.2 million new HBV infections worldwide each year.

4 Dec 2024

LysoTRAP Strategy Offers Hope for Clearing Viral Infections Across Variants

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a novel lysosomal strategy for clearing viruses and their variants.

28 Nov 2024

Reduced Protein Mobility Linked to Chronic Diseases and Their Complications

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

28 Nov 2024