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New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

Study uncovers how the immune system generates effective antibodies

An in-depth Garvan study of how the immune system generates effective antibodies provides new insights for vaccine design.

25 Aug 2020

New approach could slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

25 Aug 2020

STING protein activates a pathway that kills tumor-fighting immune cells

The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, one that directly kills tumor-fighting immune cells.

25 Aug 2020

Study shows Annexin molecule promotes resistance to anticancer drugs

Headed by Kumamoto University (Japan), a collaborative study has identified a novel mechanism for anticancer drug resistance in gastric cancer.

24 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Newly discovered molecule can help develop anticancer treatments

A molecule recently discovered by scientists can trigger a natural immune-boosting protein, known as STING (short for STimulator of INterferon Genes).

24 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

A metabolic enzyme could be potential target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

21 Aug 2020

Study explains how epigenetic factors relate to aging

According to a study, headed by a psychologist at the University of California, genetic background may influence how people adapt to aging in late life.

20 Aug 2020

Researchers solve debate on molecular events involved in the process of respiration

Respiration is essentially a rudimentary process that occurs in all living things, enabling them to create energy, remain healthy, and live.

20 Aug 2020

Elevated levels of heart failure marker increase risk for diabetes-related complications

Healthy people - especially women - with elevated levels of the heart failure marker NT-proBNP have a lower risk of developing type 2 diabetes.

19 Aug 2020

RNA-based therapeutic approach could be used to cure hereditary diseases

Short RNA molecules can be used as medication. Their effectiveness is based on the genetic information they carry: therapeutic RNA can bind to the body's own RNA and thus influence how it functions.

19 Aug 2020

New technique could accelerate drug research for various diseases

Alicyclic compounds are groups of organic chemical compounds that have led to the development of a number of medications.

19 Aug 2020

Study shows how proteins act as a defense mechanism to protect their own DNA

Viruses usually inject their DNA into a host cell to multiply. As soon as this foreign material penetrates the intracellular fluid, it activates a defense mechanism called the cGAS-STING pathway.

18 Aug 2020

High-speed AFM enables real-time visualization of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

18 Aug 2020

Researchers identify a novel interaction in hydrogenases

Hydrogenases can convert hydrogen just as efficiently as expensive platinum catalysts. In order to make them usable for biotechnological applications, researchers are deciphering how they work in detail.

18 Aug 2020

Sustainable biotechnological production of coral antibiotic

Thomas Brück saw the sea whip Antillogorgia elisabethae for the first time 17 years ago while diving on a research trip to the Bahamas.

18 Aug 2020

Harnessing natural enzymes to create complex, oxygen-containing molecules

Chemists at Scripps Research have efficiently created three families of complex, oxygen-containing molecules that are normally obtainable only from plants.

14 Aug 2020

Scientists discover gut bacteria’s role in battling cancerous tumors

Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine (CSM) have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it.

14 Aug 2020